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Volume 29, Number 7—July 2023
Research

Triplex ELISA for Assessing Durability of Taenia solium Seropositivity after Neurocysticercosis Cure

Nina L. Tang, Theodore E. Nash, Madelynn Corda, Thomas B. Nutman, and Elise M. O’ConnellComments to Author 
Author affiliation: National Institutes of Health, Bethesda, Maryland, USA

Main Article

Figure 4

Positivity patterns per cyst location for a triplex assay to determine durability of Taenia solium seropositivity after neurocysticercosis cure. The assay combines 3 families of T. solium antigens: A) T24H; B) GP50; and C) Ts18var3. Graphs display signal-to-noise reactivity to T24H, GP50, and Ts18var3 by neurocysticercosis disease type. We assessed differential reactivity to T. solium antigens in samples from 68 neurocysticercosis-positive persons, 17 with parenchymal, 16 with ventricular, and 35 with subarachnoid neurocysticercosis. Dotted horizontal lines indicate 100% specificity cutoff each protein. NS, not statistically significant; P, parenchymal; S, subarachnoid; V, ventricular.

Figure 4. Positivity patterns per cyst location for a triplex assay to determine durability of Taenia solium seropositivity after neurocysticercosis cure. The assay combines 3 families of T. solium antigens: A) T24H; B) GP50; and C) Ts18var3. Graphs display signal-to-noise reactivity to T24H, GP50, and Ts18var3 by neurocysticercosis disease type. We assessed differential reactivity to T. solium antigens in samples from 68 neurocysticercosis-positive persons, 17 with parenchymal, 16 with ventricular, and 35 with subarachnoid neurocysticercosis. Dotted horizontal lines indicate 100% specificity cutoff each protein. NS, not statistically significant; P, parenchymal; S, subarachnoid; V, ventricular.

Main Article

Page created: May 08, 2023
Page updated: June 20, 2023
Page reviewed: June 20, 2023
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