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Volume 30, Number 12—December 2024
Research

Cost-effectiveness Analysis of Japanese Encephalitis Vaccination for Children <15 Years of Age, Bangladesh

An Nguyen1, Rebeca Sultana1Comments to Author , Elisabeth Vodicka, Zareen Tasnim, Kamran Mehedi, Md. Monjurul Islam, S.M. Abdullah Al Murad, Md. Redowan Ullah, Sharmin Sultana, Tahmina Shirin, and Clint Pecenka
Author affiliation: Program for Appropriate Technology in Health (PATH), Ho Chi Minh City, Vietnam (A. Nguyen); icddr,b, Dhaka, Bangladesh (R. Sultana, Z. Tasnim, M.R. Ullah); PATH, Seattle, Washington, USA (E. Vodicka, C. Pecenka); PATH, Dhaka (K. Mehedi); Maternal, Newborn, Child and Adolescent Health, Dhaka (M.M. Islam, S.M.A. Al Murad); Institute of Epidemiology Diseases Control and Research, Dhaka (S. Sultana, T. Shirin)

Main Article

Table 2

Summary of model parameters for costs of Japanese encephalitis vaccine delivery and Japanese encephalitis treatment, Bangladesh, 2023*

Parameter
 Base case estimate
Range
 Source
Japanese encephalitis treatment costs, US $
Japanese encephalitis-related hospitalization costs per event
Direct medical cost to health system 106 77–135 (18)
Medical and non-medical cost to household 487 415–559 (18)
Indirect cost to household 351 254–448 (18)
Annual sequelae costs to health system
Mild 6 0–14 (18)
Moderate 84 0–201 (18)
Severe 83 15–150 (18)
Annual sequelae costs to household
Mild 213 71–355 (18)
Moderate 705 458–952 (18)
Severe
 846
 552–1,140
 (18)
Vaccine-related costs
Vaccine, adverse events, and supplies cost to government, per dose, US $ 0.50 0.40–0.59 (37; S. Najibullah, unpub. data, internal report, 2023 Sep 16)
Annual increase in vaccine cost, % 5 4–6 Assumption
Vaccine delivery cost per dose for routine immunization, US $ 1.71 1.37–2.05 (S. Najibullah, unpub. data, internal report, 2023 Sep 16)
Vaccine delivery cost per dose for campaign-based delivery, US $ 1.10 0.88–1.32 (41)
Wastage, % 10 8–12 In-country expert opinion
Buffer, % 10 8–12 In-country expert opinion

*Costs are given in 2001 US dollars (US $).

Main Article

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Main Article

1These first authors contributed equally to this article.

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