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Volume 30, Number 12—December 2024
Research

Human Circovirus in Patients with Hepatitis, Hong Kong

Shusheng Wu1, Cyril Chik-Yan Yip1, Jianwen Situ1, Zhiyu Li, Stanley Siu-Fung Ho, Jianpiao Cai, Jane Hau-Ching Poon, Nicholas Foo-Siong Chew, Jonathan Daniel Ip, Tom Wai-Hin Chung, Kelvin Hei-Yeung Chiu, Anna Jinxia Zhang, Estie Hon-Kiu Shun, James Yiu-Hung Tsoi, Jade Lee-Lee Teng, David Christopher Lung, Kelvin Kai-Wang To, Vincent Chi-Chung Cheng, Irene Oi-Lin Ng, Kwok-Yung Yuen, and Siddharth SridharComments to Author 
Author affiliation: The University of Hong Kong, Hong Kong, China (S. Wu, C.C.-Y. Yip, J. Situ, Z. Li, S.S.-F. Ho, J. Cai, J.H.-C. Poon, N.F.-S. Chew, J.D. Ip, A.J. Zhang, J.Y.-H. Tsoi, J.L.-L. Teng, K.K.-W. To, V.C.-C. Cheng, I.O.-L. Ng, K.-Y. Yuen, S. Sridhar); Queen Mary Hospital, Hong Kong (T.W.-H. Chung, K.H.-Y. Chiu, V.C.-C. Cheng); Queen Elizabeth Hospital, Hong Kong (D.C. Lung); Hong Kong Children's Hospital, Hong Kong (D.C. Lung); Centre for Virology, Vaccinology and Therapeutics, Hong Kong (E.H.-K. Shun, K.K.-W. To, K.Y. Yuen)

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Figure 6

Cell-binding assay showing binding of HCirV VLPs to PLC/PRF/5 cells in study of HCirV in patients with hepatitis. HEV VLPs (bHEV p239) is included as a positive control; SARS-CoV-2 NP protein is included as a negative control. Nuclei are counterstained with DAPI. Cap, capsid; HCirV, human circovirus; HEV, hepatitis E virus; NP, nucleoprotein; VLP, virus-like particle.

Figure 6. Cell-binding assay showing binding of HCirV VLPs to PLC/PRF/5 cells in study of HCirV in patients with hepatitis. HEV VLPs (bHEV p239) is included as a positive control; SARS-CoV-2 NP protein is included as a negative control. Nuclei are counterstained with DAPI. Cap, capsid; HCirV, human circovirus; HEV, hepatitis E virus; NP, nucleoprotein; VLP, virus-like particle.

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1These authors contributed equally to this article.

Page created: October 04, 2024
Page updated: November 26, 2024
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