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Volume 30, Number 12—December 2024
Research

Human Circovirus in Patients with Hepatitis, Hong Kong

Shusheng Wu1, Cyril Chik-Yan Yip1, Jianwen Situ1, Zhiyu Li, Stanley Siu-Fung Ho, Jianpiao Cai, Jane Hau-Ching Poon, Nicholas Foo-Siong Chew, Jonathan Daniel Ip, Tom Wai-Hin Chung, Kelvin Hei-Yeung Chiu, Anna Jinxia Zhang, Estie Hon-Kiu Shun, James Yiu-Hung Tsoi, Jade Lee-Lee Teng, David Christopher Lung, Kelvin Kai-Wang To, Vincent Chi-Chung Cheng, Irene Oi-Lin Ng, Kwok-Yung Yuen, and Siddharth SridharComments to Author 
Author affiliation: The University of Hong Kong, Hong Kong, China (S. Wu, C.C.-Y. Yip, J. Situ, Z. Li, S.S.-F. Ho, J. Cai, J.H.-C. Poon, N.F.-S. Chew, J.D. Ip, A.J. Zhang, J.Y.-H. Tsoi, J.L.-L. Teng, K.K.-W. To, V.C.-C. Cheng, I.O.-L. Ng, K.-Y. Yuen, S. Sridhar); Queen Mary Hospital, Hong Kong (T.W.-H. Chung, K.H.-Y. Chiu, V.C.-C. Cheng); Queen Elizabeth Hospital, Hong Kong (D.C. Lung); Hong Kong Children's Hospital, Hong Kong (D.C. Lung); Centre for Virology, Vaccinology and Therapeutics, Hong Kong (E.H.-K. Shun, K.K.-W. To, K.Y. Yuen)

Main Article

Table 1

Clinical and demographic characteristics of hepatitis cases and asymptomatic controls in study of human circovirus in patients with hepatitis, Hong Kong

Characteristic Hepatitis cases, n = 278 Controls, n = 184
Median age, y (IQR)
 59 (46–69)
 53; 38.8 – 61
Sex
M 143 (51.4) 96 (52.2)
F
 135 (48.6)
 88 (47.8)
Immunosuppression 95 (34.2) 117 (63.6)
Hemopoietic stem cell transplant 24 32
Solid organ transplant 43 67
HIV 1 1
Hematological malignancy 14 14
Cancer/chemotherapy 8 0
Other
5
 3
Median ALT, U/L (IQR) 126 (66.3–267.3) NA
Median ALP, U/L (IQR) 142 (97–240) NA
Median total bilirubin, µmol/L (IQR) 12 (8–30) NA

*Values are no. (%) except as indicated. ALP, alkaline phosphatase; ALT, alanine aminotransferase; IQR, interquartile range; NA, not applicable because all liver function parameters were below the upper limit of reference ranges (Appendix Table 2).

Main Article

1These authors contributed equally to this article.

Page created: October 04, 2024
Page updated: November 26, 2024
Page reviewed: November 26, 2024
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