Volume 30, Number 8—August 2024
Research
Fatal SARS-CoV-2 Infection among Children, Japan, January–September 20221
Table 1
Results of blood examinations, drugs, and treatments after hospitalization for 27 patients in study of fatal SARS-CoV-2 infection among patients 0–19 years of age, Japan, January–September 2022*
Blood examinations at admission† | No. patients | Median (IQR) | Reference range |
---|---|---|---|
Leukocytes, no./μL | 12 | 9,200 (6,270–14,450) | 4,100–16,300 |
Neutrophils, % | 11 | 65.7 (32.6–76.0) | 18–94 |
Lymphocytes, % | 11 | 27.0 (11.4–32.3) | 18–82 |
Hemoglobin, g/dL | 12 | 13.4 (12.8–14.5) | 11.5–14.4 |
Hematocrit, % | 12 | 41.2 (38.9–44.6) | 34.5–43.0 |
Platelets, 104/μL | 12 | 19.4 (15.0–25.7) | 18.0–51.0 |
PT-INR | 5 | 1.32 (1.23–1.60) | 0.75–1.15 |
Fibrinogen, mg/dL | 6 | 186 (144–244) | 200–400 |
D-dimer, ng/dL | 5 | 39.3 (27.3–79.7) | 0.15–1.0 |
Albumin, g/dL | 10 | 4.6 (4.1–4.8) | 3.6–4.7 |
Total bilirubin, mg/dL | 7 | 0.31 (0.30–0.80) | 0.3–0.9 |
Alanine aminotransferase, U/L | 12 | 47 (25.5–274.5) | 9–28 |
Aspartate aminotransferase, U/L | 12 | 61 (42–322) | 24–38 |
Lactate dehydrogenase, U/L | 11 | 397 (254–738) | 175–320 |
Creatine kinase, U/L | 10 | 83.5 (62–201) | 46–230 |
C-reactive protein, mg/dL | 12 | 0.31 (0.11–0.47) | 0.0–0.3 |
Sodium, mmol/L | 12 | 137 (135–142) | 137–144 |
Potassium, mmol | 12 | 4.5 (3.7–5.3) | 3.6–4.7 |
Glucose, mg/dL | 9 | 171 (138–236) | 70–200 |
Blood urea nitrogen, mg/dL | 12 | 15.9 (13.8–19.5) | 6.6–19.6 |
Creatinine, mg/dL | 12 | 0.61 (0.42–1.38) | 0.25–0.34 |
Lactate, mmol/L | 9 | 4.8 (4.2–9.7) | 0.5–2.0 |
*Reference ranges are for persons 6 years of age. IQR: interquartile range, PT-INR, prothrombin time international normalized ratio. †Excludes patients who died before admission to hospital and those with out-of-hospital cardiac arrest.
1Preliminary results from this study were presented in Japanese as a government surveillance report at https://www.niid.go.jp/niid/ja/2019-ncov/2559-cfeir/11727-20.html.
2These first authors contributed equally to this article.
3Members of the COVID-19 Fatal Pediatric Cases Database Group who contributed data are listed at the end of this article.