Volume 30, Number 8—August 2024
Research
Fatal SARS-CoV-2 Infection among Children, Japan, January–September 20221
Table 3
Characteristics of 16 patients for whom central nervous system abnormalities were suspected of causing death in study of fatal SARS-CoV-2 infection among patients 0–19 years of age, Japan, January–September 2022*
Characteristics | Value |
---|---|
Age group, y | |
0 | 0 |
1–4 | 5 (31) |
5–11 | 9 (56) |
12–19 |
2 (13) |
Sex | |
M | 8 (50) |
F |
8 (50) |
Underlying disease | |
Yes | 5 (31) |
No |
11 (69) |
Vaccination | |
None | 11 (69) |
Ineligible |
5 (31) |
Symptoms/signs | |
Fever | 14 (88) |
Disturbance of consciousness | 13 (81) |
Seizure | 11 (69) |
Nausea/vomiting | 8 (50) |
Headache |
6 (38) |
OHCA | |
Yes | 3 (19) |
No |
13 (81) |
Days from symptom onset to first consultation | |
0–2 | 16 (100) |
>3 | 0 |
Median (IQR) |
0.5 (0–1.0) |
Days from symptom onset to cardiopulmonary arrest | |
0–4 | 11 (69) |
5–9 | 0 |
>10 | 5 (31) |
Median (IQR) |
2.0 (1.0–12.0) |
Days from symptom onset to death | |
0–4 | 9 (56) |
5–9 | 0 |
>10 | 7 (44) |
Median (IQR) | 3.5 (2.0–14.5) |
*Values are no. (%) patients except as indicated. OHCA, out-of-hospital cardiac arrest, IQR, interquartile range.
1Preliminary results from this study were presented in Japanese as a government surveillance report at https://www.niid.go.jp/niid/ja/2019-ncov/2559-cfeir/11727-20.html.
2These first authors contributed equally to this article.
3Members of the COVID-19 Fatal Pediatric Cases Database Group who contributed data are listed at the end of this article.