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Volume 30, Number 9—September 2024
Research

Autochthonous Leishmaniasis Caused by Leishmania tropica, Identified by Using Whole-Genome Sequencing, Sri Lanka

Hermali Silva1, Tiago R. Ferreira1, Kajan Muneeswaran, Sumudu R. Samarasinghe, Eliza V.C. Alves-Ferreira, Michael E. Grigg, Naduviladath V. Chandrasekharan, David L. Sacks, and Nadira D. KarunaweeraComments to Author 
Author affiliations: University of Colombo, Colombo, Sri Lanka (H. Silva, K. Muneeswaran, S.R. Samarasinghe, N.V. Chandrasekharan, N.D. Karunaweera); Laboratory of Parasitic Diseases, National Institutes of Health, Bethesda, Maryland, USA (T.R. Ferreira, E.V.C. Alves-Ferreira, M.E. Grigg, D.L. Sacks)

Main Article

Figure 5

Phylogenetic network of all Leishmania isolates from Sri Lanka and Old World strains analyzed and visualized as a splits tree built using genomewide single-nucleotide polymorphisms in SplitsTree 6 (17). A) The cluster of the L. donovani complex is found at the top of the tree (blue) and the L. tropica are found at the bottom (orange). B) Phylogenetic network analysis of only the L. tropica genomes in our dataset. Orange squares, L. tropica isolates from Sri Lanka (HS1, H9–34); black font, Middle Eastern L. tropica; gray font, Azerbaijan (SAFK27) (8), Morocco (Ltr16) (21), and Afghanistan (Rupert) (8); red font, Indian L. tropica (K26 and K112) (8). Scale bar represents nucleotide substitutions per position.

Figure 5. Phylogenetic network of all Leishmania isolates from Sri Lanka and Old World strains analyzed and visualized as a splits tree built using genomewide single-nucleotide polymorphisms in SplitsTree 6 (17). A) The cluster of the L. donovani complex is found at the top of the tree (blue) and the L. tropica are found at the bottom (orange). B) Phylogenetic network analysis of only the L. tropica genomes in our dataset. Orange squares, L. tropica isolates from Sri Lanka (HS1, H9–34); black font, Middle Eastern L. tropica; gray font, Azerbaijan (SAFK27) (8), Morocco (Ltr16) (21), and Afghanistan (Rupert) (8); red font, Indian L. tropica (K26 and K112) (8). Scale bar represents nucleotide substitutions per position.

Main Article

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Main Article

1These authors contributed equally to this article.

Page created: August 07, 2024
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