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Volume 30, Number 9—September 2024
Dispatch

Avian and Human Influenza A Virus Receptors in Bovine Mammary Gland

Charlotte KristensenComments to Author , Henrik E. Jensen, Ramona Trebbien, Richard J. Webby, and Lars E. Larsen
Author affiliations: University of Copenhagen, Frederiksberg, Denmark (C. Kristensen, H.E. Jensen, L.E. Larsen); Statens Serum Institut, Copenhagen, Denmark (R. Trebbien); St. Jude Children’s Research Hospital, Memphis, Tennessee, USA (R.J. Webby)

Main Article

Table

The average percentage of epithelial staining of the human and duck influenza A virus receptors in the alveoli and ducts in 9 cows with different breeds, ages, and parity status*.

Breed Age, y Parity Lactation† % SNA
% MAA-II, alveoli‡
Alveoli Ducts
Jersey
6
4
Late
53
18
37
Danish Holstein 4 2 Late 57 3 47
7 5 Late 40 21 46
6 4 Early/mid 47 4 44
5 2 Late 58 24 61
6 4 Early/mid 51 10 49
5 3 Early/mid 55 1 51

4
3
Late
52
32
48
Unknown
Unknown
Unknown
Early/mid
59
6
47
Average 5 3 NA 54 13 48

*MAA-II, duck receptor; NA, not applicable; SNA, human receptor. †All images were obtained from active alveoli of the mammary glands and the staining is therefore not representative for the whole section of cows in late lactation. The lactation period was determined by investigating the luminal size of the alveoli and the amount of connective tissue (12). ‡The staining did not exceed the amount of staining observed with the neuraminidase treatment, suggesting a nonspecific staining in the ducts.

Main Article

Page created: July 17, 2024
Page updated: August 21, 2024
Page reviewed: August 21, 2024
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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