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Volume 31, Number 1—January 2025
Dispatch

Fatal Case of Crimean-Congo Hemorrhagic Fever, Portugal, 2024

Líbia Zé-Zé1Comments to Author , Cristina Nunes1, Micaela Sousa, Rita de Sousa, Carla Gomes, Ana S. Santos, Rui T. Alexandre, Fátima Amaro, Tiago Loza, Miriam Blanco, and Maria J. Alves
Author affiliation: National Institute of Health Doutor Ricardo Jorge, Águas de Moura, Portugal (L. Zé-Zé, R. de Sousa, A.S. Santos, F. Amaro, M.J. Alves); Center for the Study of Animal Science, Porto, Portugal (L. Zé-Zé, F. Amaro, M.J. Alves); Northeastern Local Health Unit, Bragança, Portugal (C. Nunes, M. Sousa, C. Gomes, R.T. Alexandre, T. Loza, M. Blanco); Environmental Health Institute, Lisboa, Portugal (A.S. Santos, F. Amaro, M.J. Alves)

Main Article

Table 2

Laboratory data for patient in fatal case of Crimean-Congo hemorrhagic fever, Portugal, 2024*

Category (reference limit range)
 D2
 D6
 D7
 D8
 D9
 D10
 D11
Hemoglobin, g/dL (14.0–17.5)
 12.9
 11.6
 10.5
 11.6
 10.6
 9.4
 8.8
Leukocytes, 109 cells/L (4.4–11.3)
 7.83
 5.95
 4.50
 4.83
 3.64
 2.94
 2.36
Neutrophils, 109 cells/L
 7.44
 4.22
 3.11
 3.10
 2.82
 2.29
 1.82
Lymphocytes, 109 cells/L
 0.24
 1.49
 1.22
 1.56
 0.71
 0.57
 0.50
Platelet count, 109/L (150–450)
 156
 6
 5
 7
 13
 14
 10
C-reactive protein, mg/dL
 0.15
 3.44
 1.95
 1.57
 0.75
 0.66
 1.03
Prothrombin time, s (9.4–12.5)
 11.5
 11.2
 11
 10.9
 12.7
 14.1
 15.1
Activated partial thromboplastin time, s (25.1–36.5)
 23.6
 53.9
 52.7
 56.6
 48.0
 44.3
 47.7
Fibrinogen, mg/dL
 275
 NT
 NT
 125
 135
 129
 NT
Aspartate aminotransferase, IU/L (<35)
 31
 545
 549
 1,259
 7,547
 7,644
 8,330
Alanine aminotransferase,e IU/L (<45)
 19
 141
 149
 370
 2,272
 2,471
 2,659
Total bilirubin, mg/dL (0.3–1.2)
 NT
 0.81
 0.93
 1.49
 2.57
 3.92
 5.34
Creatine kinase, IU/L (<171)
 NT
 372
 NT
 263
 262
 246
 397
Lactate dehydrogenase, IU/L (<248)
 285
 2,278
 1,879
 2,495
 8,655
 9,712
 10,980
Urine cultures
 NT
 Neg
 NT
 Neg
 NT
 NT
 NT
Blood cultures Neg Neg NT Neg NT NT NT

*CCHFV, Crimean-Congo hemorrhagic fever virus; D, day after symptom onset; Neg, negative; NT, not tested; Pos, positive.

Main Article

1These first authors contributed equally to this article.

Page created: November 15, 2024
Page updated: December 22, 2024
Page reviewed: December 22, 2024
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