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Persistence of SARS-CoV-2 Alpha Variant in White-Tailed Deer, Ohio, USA
Natalie N. Tarbuck
1, Sofya K. Garushyants
1, Dillon S. McBride, Patricia M. Dennis, John Franks, Karlie Woodard, Austin Shamblin, Michael G. Sovic, Derek T. Collins, Kyle Van Why, Richard J. Webby, Martha I. Nelson, and Andrew S. Bowman
Author affiliation: The Ohio State University, Columbus, Ohio, USA (N.N. Tarbuck, D.S. McBride, P.M. Dennis, A. Shamblin, M.G. Sovic, A.S. Bowman); National Institutes of Health, Bethesda, Maryland, USA (S.K. Garushyants, M.I. Nelson); Cleveland Metroparks Zoo, Cleveland, Ohio, USA (P.M. Dennis); St. Jude Children's Research Hospital, Memphis, Tennessee, USA (J. Franks, K. Woodard, R.J. Webby); Animal and Plant Health Inspection Service, Fort Collins, Colorado, USA (D.T. Collins); Animal and Plant Health Inspection Service, Harrisburg, Pennsylvania, USA (K. Van Why).
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Figure 4

Figure 4. Mutations in the spike glycoprotein of SARS-CoV-2 viruses circulating in white-tailed deer in northeast Ohio, USA. SARS-CoV-2 spike glycoprotein structure obtained from the Protein Data Base (identification no. 7jji; https://www.rcsb.org). RBD and NTD are labeled. Circles indicate the location of mutations in the SARS-CoV-2 clade B.1.1.7 viruses collected from white-tailed deer in Ohio and other US states: red, L18F; orange, T22I; pink, A982S. Mutation S12F (located in NTD) is not shown because it is located at the flexible N-terminus for, which a 3D structure is not available. NTD, N-terminal domain; RBD, receptor-binding domain.
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Page created: May 13, 2025
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