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Volume 31, Number 7—July 2025
Dispatch
Outbreak of Ceftriaxone-Resistant Salmonella enterica Serovar Typhi, Bangladesh, 2024
Yogesh Hooda, Arif Mohammad Tanmoy, Sudipta Deb Nath, Anannya Barman Jui, Al Amin, Hafizur Rahman, Neoyman Nasir Shorkar, Naito Kanon, Md Asadur Rahman, Denise O. Garrett, Mohammad Shahidul Islam, Nawshad Uddin Ahmed ASM, Samir K. Saha, and Senjuti Saha
Table
Clinical, demographic, and epidemiologic features of patients with ceftriaxone-resistant Salmonella enterica serovar Typhi 4.3.1.2.B1 infections based on data from an outbreak in Bangladesh, 2024
| Characteristic | No. (%) patients, n = 21 |
|---|---|
| Sex | |
| M | 15 (72) |
| F |
6 (28) |
| Age, y | |
| 1–5 | 7 (33) |
| 6–10 | 3 (14) |
| 11–15 | 4 (19) |
| 16–20 | 3 (14) |
| 21–25 | 2 (10) |
| >25 |
2 (10) |
| Clinical characteristics | |
| Fever | 21 (100) |
| Headache | 11 (52) |
| Cough | 10 (47) |
| Abdominal pain | 11 (52) |
| Breathing difficulty | 3 (14) |
| Vomiting | 7 (33) |
| Diarrhea | 6 (28) |
| Jaundice* | 1 (5) |
| Nausea | 2 (10) |
| Anorexia |
2 (10) |
| Treatment outcome | |
| Recovered |
21 (100) |
| Treatment location | |
| Outpatient department | 14 (67) |
| Inpatient department |
7 (33) |
| Initial antibiotic received | |
| Third-generation cephalosporin | 12 (57) |
| Cefixime | 7 (30) |
| Ceftriaxone | 4 (19) |
| Ceftibuten | 1 (5) |
| Second-generation cephalosporin: cefuroxime | 1 (5) |
| Azithromycin | 4 (19) |
| Ciprofloxacin | 1 (5) |
| Ciprofloxacin + azithromycin | 1 (5) |
| Tazobactam/piperacillin | 1 (5) |
| Unknown |
1 (5) |
| Second antibiotic received | |
| Third-generation cephalosporin: ceftriaxone | 2 (10) |
| Meropenem | 5 (24) |
| Azithromycin | 1 (5) |
| Amoxicillin/clavulanic acid, amikacin | 1 (5) |
| Ttrimethoprim/sulfamethoxazole | 1 (5) |
| Unknown | 1 (5) |
*Participant had concomitant hepatitis A virus infection.
Page created: June 02, 2025
Page updated: June 20, 2025
Page reviewed: June 20, 2025
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