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Volume 31, Number 8—August 2025

Perspective

A Roadmap of Primary Pandemic Prevention Through Spillover Investigation

Emily S. GurleyComments to Author  and Raina K. Plowright
Author affiliation: Johns Hopkins University, Baltimore, Maryland, USA (E.S. Gurley); Cornell University, Ithaca, New York, USA (R.K. Plowright).

Main Article

Figure 1

A visual guide to One Health investigations of spillovers to assist with primary pandemic prevention. One Health investigations trace spillover events backward from detection, systematically uncovering the causal chain that led to spillover. This process involves characterizing the pathogen, contexts, and risks for transmission and determining the reservoir hosts and environmental conditions that enabled the event.

Figure 1. A visual guide to One Health investigations of spillovers to assist with primary pandemic prevention. One Health investigations trace spillover events backward from detection, systematically uncovering the causal chain that led to spillover. This process involves characterizing the pathogen, contexts, and risks for transmission and determining the reservoir hosts and environmental conditions that enabled the event.

Main Article

Page created: July 02, 2025
Page updated: July 21, 2025
Page reviewed: July 21, 2025
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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