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Volume 31, Number 9—September 2025

Dispatch

Rapidly Progressing Melioidosis Outbreak in City Center Zoo, Hong Kong, 2024

Christopher J. Brackman1, Ivan Tak-Fai Wong1, Allen S.L. Chan1, Patrick C.K. Pun, Dorothy Hong-Ting Cheung, Anne C.N. Tse, Carlton P.M. Yuen, Pierra Y.T. Law, Wing-Yin Tam, Franklin Wang-Ngai ChowComments to Author , Gilman Kit-Hang Siu, and Thomas Hon-Chung SitComments to Author 
Author affiliation: Government of the Hong Kong Special Administrative Region, Hong Kong, China (C.J. Brackman, A.S.L. Chan, P.C.K. Pun, A.C.N. Tse, C.P.M Yuen, P.Y.T. Law, T.H.-C. Sit); Polytechnic University, Hong Kong (I.T.-F. Wong, D.H.-T. Cheung, W.-Y. Tam, F.W.-N. Chow, G.K.-H. Siu)

Main Article

Figure 2

Phylogenetic analysis of Burkholderia pseudomallei ST46 genomes from nonhuman primates that died during rapidly progressing melioidosis outbreak in city center zoo, Hong Kong, 2024. Tree compares case nos. 01−11 with 40 reference genomes acquired globally from NCBI. Maximum-likelihood phylogenies of the single-nucleotide polymorphisms of the 3,127 single-copy cgMLSTs are shown. Bootstrap analysis of 1,000 replicates was performed, and bootstrap values of selected nodes are shown. The tree is midpoint rooted. The 11 monkey isolates formed a monophyletic clade with 100% bootstrap confidence. Distinct colors are used as a visual aid to group isolates by their MLST, cgMLST, and geographic location. Scale bar indicates nucleotide substitutions per site. cgMLST, core-genome MLST; MLST, multilocus sequence typing; ST, sequence type.

Figure 2. Phylogenetic analysis of Burkholderia pseudomallei ST46 genomes from nonhuman primates that died during rapidly progressing melioidosis outbreak in city center zoo, Hong Kong, 2024. Tree compares case nos. 01−11 with 40 reference genomes acquired globally from NCBI. Maximum-likelihood phylogenies of the single-nucleotide polymorphisms of the 3,127 single-copy cgMLSTs are shown. Bootstrap analysis of 1,000 replicates was performed, and bootstrap values of selected nodes are shown. The tree is midpoint rooted. The 11 monkey isolates formed a monophyletic clade with 100% bootstrap confidence. Distinct colors are used as a visual aid to group isolates by their MLST, cgMLST, and geographic location. Scale bar indicates nucleotide substitutions per site. cgMLST, core-genome MLST; MLST, multilocus sequence typing; ST, sequence type.

Main Article

1These authors contributed equally to this article.

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