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Volume 32, Number 10—October 2026
Dispatch
Emergence of Macrolide-Resistant Bordetella pertussis, Peru, 2025
Eduardo Juscamayta-López
, Faviola Valdivia, Carmen Rodríguez-Cueva, Helen Horna, Yaneth Quispe, María Pía Soto, Segundo Torres, Victor Fiestas Solórzano, Martin Yagui, Vlademir Vicente Cantarelli, Efrain Montilla-Escudero, Víctor Silva, and Ana Raquel Da Costa
, Faviola Valdivia, Carmen Rodríguez-Cueva, Helen Horna, Yaneth Quispe, María Pía Soto, Segundo Torres, Victor Fiestas Solórzano, Martin Yagui, Vlademir Vicente Cantarelli, Efrain Montilla-Escudero, Víctor Silva, and Ana Raquel Da Costa
Table
Characteristics of patients with culture-confirmed Bordetella pertussis carrying the macrolide-resistant A2047G mutation in the 23S rRNA gene, Peru, 2025
| Sample no. | Year of collection | Age/sex | Region, Province | Vaccine status† | Maternal Tdap‡ | Antimicrobial drug treatment | Hospitalized |
|---|---|---|---|---|---|---|---|
| tf518-24* | 2024 | 9 mo/F | Loreto, Datem del Marañón | 2 doses | Unknown | No | Unknown |
| tf048-25 | 2025 | 1.6 y/M | Puno, Melgar | Unknown | No | No | Yes |
| tf098-25 | 2025 | 3 mo/F | Lima, Callao | 0 | No | Azithromycin | Yes |
| tf120-25 | 2025 | 39.5 y/F | Lima, Callao | Unknown | No | Unknown | Unknown |
| tf232-25 | 2025 | 16 y/M | Cusco, Cusco | 1 dose | No | Azithromycin | Unknown |
| tf303-25 | 2025 | 1 mo/F | Arequipa, Arequipa | 0 | Unknown | Azithromycin, ampicillin, and amikacin | Yes |
| tf353-25 | 2025 | 7 mo/M | Cusco, Cusco | 3 doses | Yes | Azithromycin | Unknown |
*This isolate, collected in late 2024, was considered part of the early phase of the 2025 outbreak. †Number of diphtheria–tetanus–whole cell pertussis–hepatitis B–Hemophilus influenzae type b vaccine doses received before illness onset. ‡Tdap (tetanus–diphtheria–acellular pertussis) vaccination during pregnancy in the patient’s mother.
Page created: July 21, 2026
Page updated: September 16, 2026
Page reviewed: September 16, 2026
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