Volume 32, Number 10—October 2026
Research
Genomic Epidemiology of Salmonella enterica Serovar Hadar Strain Linked to Poultry-Associated Salmonellosis Outbreaks, United States
Lingzi Xiaoli, Taylor Griswold, G. Sean Stapleton, Lee S. Katz, Zachary Ellison, Kaitlin A. Tagg, Hattie E. Webb, Katharine Benedict, and Jessica C. Chen
Table 2
Clade-defining SNP annotations for the Salmonella enterica serovar Hadar REPTDK01 subset used in genomic epidemiology study of Salmonella enterica serovar Hadar linked to poultry-associated salmonellosis outbreaks, United States†
| Gene‡ | Position | Ref | Alt | Type | Amino acid | Function | SNP prevalence, no. (%) |
χ2 test | |
|---|---|---|---|---|---|---|---|---|---|
| Clade 1 | Clade 2 | ||||||||
| pdxA | 3818146 | C | T | synonymous_variant | p.Pro271Pro | Dehydrogenase | C, 308/308 (100) | C, 2/95 (2.1) | χ2 = 385.8, p = 6.82 × 10–86 |
| T, 93/95 (97.9) |
|||||||||
| yihS | 4534475 | G | A | stop_gained | p.Trp290* | Isomerase | G, 308/308 (100) | A, 95/95 (100) | χ2 = 396.8, p = 2.78 × 10–86 |
†χ2 performed at 1 degree of freedom. Alt, nucleotide observed in sequence with the SNP mutation; Ref, nucleotide observed in the reference sequence; SNP, single-nucleotide polymorphism. ‡The reference genome used was 2021K-0017 (GenBank accession no. CP093072) from clade 1. χ2 test showed a significant difference in the distribution of the clade-defining SNP between 2 clades for each gene (p<0.05).
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