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Volume 32, Number 10—October 2026

Research

Genomic Epidemiology of Salmonella enterica Serovar Hadar Strain Linked to Poultry-Associated Salmonellosis Outbreaks, United States

Lingzi Xiaoli, Taylor Griswold, G. Sean Stapleton, Lee S. Katz, Zachary Ellison, Kaitlin A. Tagg, Hattie E. Webb, Katharine Benedict, and Jessica C. ChenComments to Author 
Author affiliation: Centers for Disease Control and Prevention, Atlanta, Georgia, USA (L. Xiaoli, T. Griswold, G.S. Stapleton, L.S. Katz, K.A. Tagg, H.E. Webb, K. Benedict, J.C. Chen); ASRT Inc., Smyrna, Georgia, USA (G. Ellison)

Main Article

Table 2

Clade-defining SNP annotations for the Salmonella enterica serovar Hadar REPTDK01 subset used in genomic epidemiology study of Salmonella enterica serovar Hadar linked to poultry-associated salmonellosis outbreaks, United States†

Gene‡ Position Ref Alt Type Amino acid Function SNP prevalence, no. (%)
χ2 test
Clade 1 Clade 2
pdxA 3818146 C T synonymous_variant p.Pro271Pro Dehydrogenase C, 308/308 (100) C, 2/95 (2.1) χ2 = 385.8, p = 6.82 × 10–86








T, 93/95 (97.9)
yihS 4534475 G A stop_gained p.Trp290* Isomerase G, 308/308 (100) A, 95/95 (100) χ2 = 396.8, p = 2.78 × 10–86

†χ2 performed at 1 degree of freedom. Alt, nucleotide observed in sequence with the SNP mutation; Ref, nucleotide observed in the reference sequence; SNP, single-nucleotide polymorphism. ‡The reference genome used was 2021K-0017 (GenBank accession no. CP093072) from clade 1. χ2 test showed a significant difference in the distribution of the clade-defining SNP between 2 clades for each gene (p<0.05).

Main Article

Page created: August 05, 2026
Page updated: September 17, 2026
Page reviewed: September 17, 2026
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