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Volume 32, Number 3—March 2026

Research

Genetically Similar High-Risk Strains of Carbapenemase-Producing Enterobacterales in Humans and Companion Animals, United States

Lingzi Xiaoli, Allison E. JamesComments to Author , Anna L. Stahl, Maho Okumura, Stephen D. Cole, Jaclyn M. Dietrich, Molly M. Leeper, Jordan K. Putney, Maroya Spalding Walters, and Richard A. Stanton
Author affiliation: Author affiliations: Centers for Disease Control and Prevention, Atlanta, Georgia, USA (L. Xiaoli, A.E. James, A.L. Stahl, M.M. Leeper, J.K. Putney, M.S. Walters, R.A. Stanton); University of Pennsylvania School of Veterinary Medicine, Philadelphia, Pennsylvania, USA (M. Okumura, S.D. Cole, J.M. Dietrich); Applied Science Research and Technology, Inc., Smyrna, Georgia, USA (J.K. Putney); US Public Health Service, Rockville, Maryland, USA (M.S. Walters)

Main Article

Figure 2

Frequency boxplots of pairwise within-cluster cgMLST allele distances among carbapenemase-producing carbapenem-resistant Enterobacterales isolates collected from humans and companion animals in study of genetically similar high-risk strains of carbapenemase-producing Enterobacterales in humans and companion animals, United States. Pairwise cgMLST allele distances were calculated between pairs within individual clusters and depicted by bacterial species with Escherichia coli (A), Klebsiella pneumoniae (B), and Enterobacter cloacae (C). Box top and bottom boundaries depict 25th and 75th quartiles, horizontal lines within boxes depict median values, dots represent individual data points, and whiskers represent datapoints within 1.5 times the interquartile range. cgMLST, core-genome multilocus sequence typing.

Figure 2. Frequency boxplots of pairwise within-cluster cgMLST allele distances among carbapenemase-producing carbapenem-resistant Enterobacterales isolates collected from humans and companion animals in study of genetically similar high-risk strains of carbapenemase-producing Enterobacterales in humans and companion animals, United States. Pairwise cgMLST allele distances were calculated between pairs within individual clusters and depicted by bacterial species with Escherichia coli (A), Klebsiella pneumoniae (B), and Enterobacter cloacae (C). Box top and bottom boundaries depict 25th and 75th quartiles, horizontal lines within boxes depict median values, dots represent individual data points, and whiskers represent datapoints within 1.5 times the interquartile range. cgMLST, core-genome multilocus sequence typing.

Main Article

Page created: February 07, 2026
Page updated: February 26, 2026
Page reviewed: February 26, 2026
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