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Volume 32, Number 6—June 2026
Research
Association of Frailty and Frailty Trajectory with Risk for Respiratory Infectious Diseases
Figure 2

Figure 2. Longitudinal baseline and follow-up associations of physical frailty with risk for RIDs. Forest plots show the trajectory of physical frailty associated with incident RIDs (A), influenza (B), OALRTI (C), and pneumonia (D). Squares indicate point estimates of HRs; error bars indicate 95% CI; dotted vertical lines indicate null effect. Analyses were adjusted for age, sex, ethnicity, education level, Townsend deprivation index, smoking status, alcohol consumption status, cumulative dietary risk factor score, PM2.5 (exposure to particulate matter <2.5 mm), nitrogen dioxide and nitrogen oxide levels, body mass index category, sleep duration, sleeplessness, and daytime dozing. HR, hazard ratio; OALRTI, other acute lower respiratory tract infection; RIDs, respiratory infectious diseases.
1These first authors contributed equally to this article.