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Volume 32, Number 6—June 2026

Dispatch

Placental Vascular Pathology Associated with Congenital Lymphocytic Choriomeningitis Virus Infection, Philadelphia, Pennsylvania, USA

Abin Abraham, Rebecca L. Linn, Dustin D. Flannery, and Scott M. GordonComments to Author 
Author affiliation: Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania, USA (A. Abraham, R.L. Linn, D.D. Flannery, S.M. Gordon); University of Pennsylvania Perelman School of Medicine, Philadelphia (R.L. Linn, D.D. Flannery, S.M. Gordon)

Main Article

Figure 1

Imaging findings for ventriculomegaly and chorioretinitis associated with congenital lymphocytic choriomeningitis virus infection, Philadelphia, Pennsylvania, USA. A–C) Case 1; D–F) case 2. A) Routine ultrasonography at 36 weeks’ gestation, demonstrating severe cerebral ventriculomegaly in the fetus (black space between markers on the anatomic right and the unmarked black space on the anatomic left). B) Postnatal (38 weeks 4 days’ gestation) brain magnetic resonance imaging of newborn confirmed severe cerebral ventriculomegaly (large, white, fluid-filled spaces bilaterally and in the center of the image). C) Fundoscopic examination of newborn, revealing multiple areas of chorioretinitis (arrows). D) Routine ultrasonography at 36 weeks’ gestation, demonstrating severe cerebral ventriculomegaly in the fetus. E) Postnatal (38 weeks 5 days’ gestation) brain magnetic resonance imaging of newborn confirmed severe cerebral ventriculomegaly. F) Fundoscopic examination of newborn, revealing a large area of chorioretinitis (arrow).

Figure 1. Imaging findings for ventriculomegaly and chorioretinitis associated with congenital lymphocytic choriomeningitis virus infection, Philadelphia, Pennsylvania, USA. A–C) Case 1; D–F) case 2. A) Routine ultrasonography at 36 weeks’ gestation, demonstrating severe cerebral ventriculomegaly in the fetus (black space between markers on the anatomic right and the unmarked black space on the anatomic left). B) Postnatal (38 weeks 4 days’ gestation) brain magnetic resonance imaging of newborn confirmed severe cerebral ventriculomegaly (large, white, fluid-filled spaces bilaterally and in the center of the image). C) Fundoscopic examination of newborn, revealing multiple areas of chorioretinitis (arrows). D) Routine ultrasonography at 36 weeks’ gestation, demonstrating severe cerebral ventriculomegaly in the fetus. E) Postnatal (38 weeks 5 days’ gestation) brain magnetic resonance imaging of newborn confirmed severe cerebral ventriculomegaly. F) Fundoscopic examination of newborn, revealing a large area of chorioretinitis (arrow).

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Page created: April 23, 2026
Page updated: May 01, 2026
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