Volume 4, Number 1—March 1998
Dispatch
Laboratory Survey of Drug-Resistant Streptococcus pneumoniae in New York City, 1993—1995
Table 1
Penicillin resistance among Streptococcus pneumoniae isolates at New York City hospital laboratories
| No. of isolates | 1993 No. (%) | 1994 No. (%) | 1995 No. (%) |
|---|---|---|---|
| Screened with oxacillin diska | 3,227 | 4,133 | 4,912 |
| zone size < 19 mmb | 273 (9) | 549 (13) | 995 (20) |
| Screened and confirmed with approved MICc | 1,229 | 2,491 | 3,535 |
| zone size < 19 mm | 154 (13) | 350 (14) | 704 (20) |
| Id | 70 (6) | 209 (8) | 310 (9) |
| Rd | 19 (2) | 115 (5) | 222 (6) |
| Sterile-site isolates screened and confirmed with MICe | 462 | 649 | 1,321 |
| I | 16 (3) | 66 (10) | 83 (6) |
| R | 5 (1) | 20 (3) | 65 (5) |
| Nonsterile isolates screened and confirmed with MICf | 456 | 662 | 1,596 |
| I | 12 (3) | 83 (13) | 200 (13) |
| R | 5 (1) | 31 (5) | 110 (7) |
aNumber of laboratories reporting oxacillin disk diffusion test results in 1993, 1994, 1995 was 33, 40, 51, respectively.
bOxacillin disk diffusion test zone size.
cApproved penicillin MIC tests include antibiotic gradient strips and broth dilution or micro-dilution using Mueller-Hinton broth supplemented with 2-5% lysed horse blood. Number of laboratories reporting MIC test results in 1993, 1994, 1995 was 10, 22, 35, respectively.
dI=Penicillin-intermediate (MIC > 0.1 and 1.0 µg/ml); R=Penicillin-resistant (MIC > 2.0 µg/ml).
eNumber of laboratories reporting sterile site isolate results in 1993, 1994, 1995 was 8, 12, 32, respectively.
fNumber of laboratories reporting nonsterile site isolate results in 1993, 1994, 1995 was 5, 9, 28, respectively.