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Volume 7, Number 3—June 2001
Synopsis

Cryptococcus neoformans Infection in Organ Transplant Recipients: Variables Influencing Clinical Characteristics and Outcome

Shahid Husain, Marilyn M. Wagener, and Nina SinghComments to Author 
Author affiliations: Veterans Affairs Medical Center and University of Pittsburgh, Thomas E. Starzl Transplantation Institute, Pittsburgh, Pennsylvania, USA

Main Article

Table 1

Variables associated with early and late-onset Cryptococcus neoformans infection in organ transplant recipients

Variable (no. of patients for whom data available) Early onset (within 12 months) (%) Late onset (>12 months) (%) p value
Age (mean) 42.2 yrs 44.3 yrs NSa
Type of transplant 0.001
Liver (20) 75 25
Kidney (54) 28 72
Heart (9) 33 67
Lung (2) 100 0
Cytomegalovirus (CMV) infection (2) 50 50 NS
No CMV infection (6) 67 33
Prior rejection (16) 50 50 NS
No prior rejection (45) 36 64
U.S. region 0.004b
Northeast (24) 67 33
West (19) 32 68
Midwest (9) 22 78
South (20) 40 60
Other countries
Europe (7) 28 71
Asia (3) 33 67
Site involved
Lung (26) 42 58 NS
Central nervous system (57) 40 60
Skin/osteoarticular (23) 30 70
Death rate (84) 34 41

aNS = not significant, p >0.05.
bNortheastern United States versus all other regions.

Main Article

Page created: April 26, 2012
Page updated: April 26, 2012
Page reviewed: April 26, 2012
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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