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Volume 7, Number 6—December 2001
Research

Advanced Age a Risk Factor for Illness Temporally Associated with Yellow Fever Vaccination

Michael Martin*†, Leisa H. Weld*, Theodore F. Tsai*, Gina T. Mootrey*, Robert T. Chen*, Manette Niu‡, Martin S. Cetron*, and the GeoSentinel Yellow Fever Working Group
Author affiliations: *Centers for Disease Control and Prevention, Atlanta, Georgia, USA;; †Emory School of Medicine, Atlanta, Georgia, USA;; ‡Center for Biologic Evaluation, U.S. Food and Drug Administration, Rockville, Maryland, USA

Main Article

Table 4

Reporting rates (RR) and reporting rate ratios (RRR) for hepatitis A vaccine adverse events by age, 1995-1998

Age (years) No. HAa doses No. OAEb OAE reports/ 100,000 doses RRR (95% CI) No. SyAEc SyAE reports/ 100,000 doses RRR (95% CI)
15-24 387,031 21 5.43 1.8(1.1-3.0) 7 1.81 0.7 (0.3-1.6)
25-44 1,444,895 44 3.05 Ref. 36 2.49 Ref.
45-64 1,096,391 23 2.10 0.7 (0.4-1.1) 26 2.37 1.0 (0.6-1.6)
65-74 241,453 4 1.66 0.5 (0.2-1.5) 15 6.21 2.5(1.4-4.6)
75 61,760 1 1.62 0.5 (0.1-3.9) 3 4.86 1.9 (0.6-6.3)
Total 3,231,530 93 2.88 87 2.69

aHA = hepatitis A [vaccine]; CI = confidence intervals; OAE = other adverse events; SyAE = systemic adverse events; Ref = reference.
bUncomplicated neurologic/systemic, hypersensitivity, or local reaction.
cMultisystemic (excluding anaphylactic) or neurologic reaction.

Main Article

1Jeff Altman, University of Washington, Seattle, Washington; Vernon Ansdell, Kaiser Permanente, Honolulu, Hawaii; Elizabeth Barnett, Boston University, Boston, Massachusetts; Michele Barry Yale University, New Haven, Connecticut; Bradley Connor, Cornell University, New York, New York; David Freedman, University of Alabama at Birmingham, Birmingham, Alabama; Alejandra Gurtman, Mount Sinai Medical Center, New York, New York; Elaine Jong, University of Washington, Seattle, Washington; Phyllis Kozarsky, Emory University, Atlanta, Georgia; Russell McMullen, University of Washington, Seattle, Washington; Jan Patterson, University of Texas, San Antonio, Texas; Bradley Sack, Johns Hopkins University, Baltimore, Maryland; Mary E. Wilson, Harvard University, Cambridge, Massachusetts; Martin Wolfe, Traveler's Medical Service of Washington, Washington, D.C.

Page created: December 09, 2010
Page updated: December 09, 2010
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The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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