Volume 7, Number 7—June 2001
International Conference on Emerging Infectious Diseases 2000
Epidemiology, Evolution, and Future of the HIV/AIDS Pandemic
|Mode of inheritance
|Initial frequency||No dominance||Dominant||Recessive|
aWe are assuming that favored genotype has a 10% advantage over the other genotypes; in the no dominance case, the relative fitness of the heterozygote is intermediate between that of the two homozygotes. With a 1% selective advantage, it would take 10 times as long for the gene to reach a frequency of 50%.