Volume 11, Number 4—April 2005
Research
Experimental Infection of Prairie Dogs with Monkeypox Virus
Shu-Yuan Xiao*, Elena Sbrana*, Douglas M. Watts*, Marina Siirin*, Amelia P.A. Travassos da Rosa*, and Robert B. Tesh*
Table 2
Monkeypox virus titers in selected tissues of experimentally infected prairie dogs at death
| Route of infection | Animal no. | Virus titer (log10 PFU/g of tissue)* |
|||||
|---|---|---|---|---|---|---|---|
| Liver | Spleen | Kidney | Lung | Heart | Brain | ||
| Intraperitoneal | MPX-1 | 8.1 | 7.2 | 4.3 | 6.7 | 0 | 0 |
| MPX-3 | 7.6 | 7.4 | 5.4 | 6.8 | 3.5 | 3.6 | |
| MPX-4 | 7.7 | 8.4 | 5.4 | 7.1 | 5.5 | NT | |
| Intranasal | MPX-5 | 0 | 0 | 0 | 0 | 0 | NT |
| MPX-6 | 0 | 0 | 0 | 0 | 0 | 4.7 | |
| MPX-7 | 0 | 0 | 0 | 0 | 0 | 0 | |
| MPX-8 | 0 | 0 | 0 | 0 | 0 | NT | |
| MPX-9 | 3.0 | 2.4 | 2.4 | 8.0 | 4.5 | 0 | |
*0, <0.7 (<100.7); NT, not tested.
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