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Volume 15, Number 5—May 2009
Research

New Respiratory Enterovirus and Recombinant Rhinoviruses among Circulating Picornaviruses

Caroline Tapparel1Comments to Author , Thomas Junier1, Daniel Gerlach, Sandra Van Belle, Lara Turin, Samuel Cordey, Kathrin Mühlemann, Nicolas Regamey, John-David Aubert, Paola M. Soccal, Philippe Eigenmann, Evgeny M. Zdobnov1, and Laurent Kaiser1
Author affiliations: University of Geneva Hospitals, Geneva, Switzerland (C. Tapparel, S. Van Belle, L. Turin, S. Cordey, P. M. Soccal, P. Eigenmann, L. Kaiser); University of Geneva Medical School, Geneva (C. Tapparel, T. Junier, D. Gerlach, S. Van Belle, L. Turin, S. Cordey, E. Zdobnov, L. Kaiser); Swiss Institute of Bioinformatics, Geneva (T. Junier, D. Gerlach, E. Zdobnov); University Hospital of Bern, Bern, Switzerland (K. Mühlemann, N. Regamey); University Hospital of Lausanne, Lausanne, Switzerland (J.-D. Aubert); Imperial College London, London, UK (E. Zdobnov); 1These authors contributed equally to this article.

Main Article

Table

Characteristics of screened study populations and respiratory samples, Switzerland*

Type of study (no. enrolled) Age group Patient characteristics Years of study Type of specimens PCR No. (%) positive Reference
Respiratory infection in newborns (243) <1 y Nonhospitalized children with initial respiratory episode with cough 1999–2005 NPS HRV-A and HRV-B specific real time for the first 203 and panenterhino for 40 36 (15) (20)
Lower respiratory tract infection in hospitalized patients (147) Adults Mainly immunocompromised patients with lower respiratory tract complications and comorbidities 2001–2003 BAL, NPS HRV-A and HRV-B specific real time 16 (11) (21)
Acute respiratory tract infection in children (653) <17 y Nonhospitalized children with AOM or pneumonia 2004–2007 NPS Panenterhino 121 (18) (22) and ongoing study
Lower respiratory tract infection in hospitalized patients (485) Adults Mainly immunocompromised patients with lower respiratory tract complications and concurrent illnesses 2003–2006 BAL, NPS Panenterhino 52 (11) (21) and ongoing study
Acute respiratory tract infection in children (64) <12 y Children at an emergency department with fever and acute respiratory symptoms treated with antimicrobial drugs 2006–2007 NPS Panenterhino 23 (36) NP
Isolation in routine procedures (NA) Children and adults Hospitalized patients 1999–2008 BAL, NPS HE culture isolation NA NP

*NPS, nasopharyngeal samples; HRV, human rhinovirus; BAL, bronchoalveolar lavage; AOM, acute otitis media; NP, not published; NA, not available; HE, human embryonic primary fibroblast cell line.

Main Article

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