Volume 15, Number 7—July 2009
Research
Relapse Associated with Active Disease Caused by Beijing Strain of Mycobacterium tuberculosis1
Table 4
Association between active disease caused by a Beijing genotype of Mycobacterium tuberculosis and relapse, by race/ethnic background, Tuberculosis Trials Consortium Study 22*
Race/ethnicity | Patients with disease that relapsed |
Relapse odds ratio (95% CI) | p value | |
---|---|---|---|---|
Infected with a Beijing strain, no. positive/no. tested (%) | Not infected with a Beijing strain, no. positive/no. tested (%) | |||
Non-Hispanic white (n = 63) | 3/11 (27) | 17/52 (33) | 0.8 (0.2–3.3) | 0.73 |
Non-Hispanic black (n = 148) | 6/22 (27) | 15/126 (12) | 2.8 (0.9–8.2) | 0.06 |
Hispanic (n = 79) | 1/7 (14) | 7/72 (9.7) | 1.5 (0.2–15) | 0.70 |
Asian–Pacific Islander (n = 50) | 4/16 (25) | 1/34 (2.9) | 11 (1.1–108) | 0.04 |
*The Tuberculosis Trials Consortium Study enrolled patients during 1995–1998. Participants in the case–control study were selected from among 1,004 HIV-infected participants. Participants of Native American race/ethnicity (n = 12) were not included because none were infected with a Beijing strain; 2 Native American participants had disease that relapsed. CI, confidence interval.
1This study was presented in part at the 2008 International Conference of the American Thoracic Society, May 16–21, 2008, Toronto, Ontario, Canada.