Volume 15, Number 9—September 2009
Research
Clinical Assessment and Improved Diagnosis of Bocavirus-induced Wheezing in Children, Finland
Maria Söderlund-Venermo
, Anne Lahtinen, Tuomas Jartti, Lea Hedman, Kaisa Kemppainen, Pasi Lehtinen, Tobias Allander, Olli Ruuskanen, and Klaus Hedman
, Anne Lahtinen, Tuomas Jartti, Lea Hedman, Kaisa Kemppainen, Pasi Lehtinen, Tobias Allander, Olli Ruuskanen, and Klaus Hedman
Table 2
Incidence rates of serologically verified acute human bocavirus infections and prevalence rates of bocavirus immunity among 258 wheezing children, Finland*
| Characteristic | Age group |
|||||||
|---|---|---|---|---|---|---|---|---|
| <6 mo | 6–<12 mo | 1–<2 y | 2–<3 y | 3–<4 y | 4–<7 y | 7–<15 y | Total | |
| Incidence | 1/26 (4) | 9/37 (24) | 25/88 (28) | 5/42 (12) | 3/25 (12) | 2/19 (10) | 0/14 (0) | 45/251 (18) |
| Prevalence | 1/21† (5) | 5/37 (13) | 28/88 (32) | 30/42 (71) | 16/25 (64) | 16/19 (84) | 14/14 (100) | 110/246† (45) |
*Values are no. positive/no. tested (%). Discrepant results of enzyme immunoassay and PCR results from 7 children were not included (see Table 1 and text).
†Five infants had maternal antibodies (defined as waning immunoglobulin G absorbance values in paired serum samples). Two other infants became seronegative and were considered virus negative.
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