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Volume 16, Number 6—June 2010
Dispatch

Xenotropic Murine Leukemia Virus–related Gammaretrovirus in Respiratory Tract

Nicole FischerComments to Author , Claudia Schulz, Kristin Stieler, Oliver Hohn, Christoph Lange, Sung Sup Park, and Martin Aepfelbacher
Author affiliations: University Medical Center Hamburg-Eppendorf, Hamburg, Germany (N. Fischer, C. Schulz, K. Stieler, M. Aepfelbacher); Robert Koch-Institute, Berlin, Germany (O. Hohn); Leibniz-Center for Medicine and Biosciences, Borstel, Germany (C. Lange); University of Bonn Medical Centre, Bonn, Germany (C. Drosten)

Main Article

Table

Detection of XMRV in respiratory tract secretions from 329 persons*

Group Patient median age, y Underlying disease Sample XMRV+
1 (75 patients with RTI) 42 None Sputum, nasal swab 3/75 (2.3%)
2 (31 patients with RTI) 60 COPD BAL 1/31 (3.2%)
3 (161 patients with RTI) 32 Immunosuppression after SOT or BMT BAL, TS 16/161 (9.9%)
Control (62 persons with no RTI) 35 None BAL, throat swab 2/62 (3.2%)

*XMRV, xenotropic murine leukemia virus; +, positive for XMRV–specific sequences by PCR; RTI, respiratory tract infection; COPD, chronic obstructive pulmonary disease; BAL, bronchoalveolar lavage; SOT, solid organ transplantation; BMT, bone marrow transplantation; TS, tracheal secretion.

Main Article

Page created: February 11, 2011
Page updated: February 11, 2011
Page reviewed: February 11, 2011
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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