Volume 16, Number 8—August 2010
Dispatch
Novel Mycobacterium tuberculosis Complex Pathogen, M. mungi
, Pete N. Laver, Anita L. Michel, Mark Williams, Paul D. van Helden, Robin M. Warren, and Nicolaas C. Gey van Pittius
Table 2
Comparison of full 24-set MIRU-VNTR of selected Mycobacterium mungi isolates*
| Sample no. |
1883 |
6601B |
6606A |
6600B |
6875 |
– |
8163/02 |
24 |
287/99 |
7739/01 |
5358/99 |
8490/00 |
H37Rv |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Year isolated |
2000 |
2002 |
2002 |
2002 |
2008 |
– |
– |
– |
– |
– |
– |
– |
– |
| Species | M. mungi | M. mungi | M. mungi | M. mungi | M. mungi | DB | M. a. | OB | M. microti | M. p. | M. caprae | M. bovis | M. t. |
| MIRU 02 | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 2 |
| VNTR 0424/ Mtub04 | 3 | 3 | 3 | 3 | 3 | 2 | 4 | 2 | 3 | 3 | 4 | 2 | 2 |
| VNTR 0577/ ETR-C | 3 | 3 | 3 | 3 | 3 | 5 | 5 | 5 | 5 | 4 | 5 | 5 | 4 |
| MIRU 04/ ETR-D | 3 | 3 | 3 | 3 | 3 | 3 | 2 | 3 | 4 | 5 | 3 | 4 | 2 |
| MIRU 40 | 1 | 1 | 1 | 1 | 1 | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 1 |
| MIRU 10 | 5 | 5 | 5 | 5 | 5 | 7 | 7 | 7 | 5 | 6 | 6 | 2 | 3 |
| MIRU 16 | 3 | 3 | 3 | 3 | 3 | 3 | 4 | 4 | 6 | 4 | 2 | 4 | 2 |
| VNTR 1955/ Mtub21 | 3 | 3 | 3 | 3 | 3 | 3 | 4 | 3 | 3 | 4 | 3 | 3 | 2 |
| MIRU 20 | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 1 | 2 | 2 | 2 | 2 |
| VNTR 2163b/ QUB11b | 0 | No | No | No | No | 7 | 5 | No | 6 | 9 | 4 | 4 | 5 |
| VNTR 2165/ ETR-A | 6 | 6 | No | 6 | 6 | 6 | 6 | 3 | 9 | 9 | 5 | 4 | 3 |
| VNTR 2347/ Mtub29 | 3 | 3 | 3 | 3 | 3 | 3 | 3 | 3 | 3 | 3 | 3 | 3 | 4 |
| VNTR 2401/ Mtub30 | 4 | 4 | 4 | 4 | 4 | 3 | 4 | 4 | 4 | 4 | 4 | 4 | 2 |
| VNTR 2461/ ETR-B | 4 | 4 | 4 | 4 | 4 | 4 | 4 | 2 | 3 | 3 | 3 | 3 | 3 |
| MIRU 23 | 4 | 4 | 4 | 4 | 4 | 4 | 4 | 4 | 4 | 4 | 4 | 4 | 6 |
| MIRU 24 | 2 | 2 | 2 | 2 | 3 | 2 | 2 | 1 | 2 | 2 | 2 | 1 | 1 |
| MIRU 26 | 4 | 4 | 3 | 3 | 4 | 5 | 4 | 4 | 2 | 2 | 4 | 3 | 3 |
| MIRU 27 | 3 | 3 | 3 | 3 | 3 | 4 | 3 | 3 | 2 | 2 | 3 | 3 | 3 |
| VNTR 3171/ Mtub34 | 3 | 3 | 3 | 3 | 3 | 3 | 3 | 3 | 3 | 3 | 2 | 3 | 3 |
| MIRU 31/ ETR-E | 8/9 | 8/9 | 8/9 | 8/9 | 8/9 | 5 | 5 | 4 | 1 | 3 | 5 | 3 | 3 |
| VNTR 3690/ Mtub39 | 2 | No | No | No | No | 5 | 4 | 4 | 3 | 3 | 1 | 2 | 5 |
| VNTR 4052/ QUB26 | No | No | No | No | No | 4 | 6 | 2 | 9 | 7 | 3 | 5 | 5 |
| VNTR 4156/ QUB4156 | No | No | No | No | No | 3 | 3 | 3 | 3 | 0 | 3 | 1 | 2 |
| MIRU 39 | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 2 |
*MIRU, mycobacterial interspersed repetitive unit; VNTR, variable number tandem repeats; DB, Dassie bacillus; M. a., M. africanum; OB, Oryx bacillus; M. p., M. pinnipedii; M. t., M. tuberculosis; –, not applicable.; no, no amplification. Gray shading highlights differences between the Mycobacterium tuberculosis complex species and M. mungi as well as variation within M. mungi samples evaluated. DB data supplied by S. Parsons. OB data supplied by P. Supply. M. africanum West African 2 strain 8163/02 (ST181), M. microti strain 287/99 (ST539), M. pinnipedii strain 7739/01, M. caprae strain 5358/99 (ST647), and M. bovis strain 8490/00 (ST482) data from www.miru-venterplus.org.