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Volume 2, Number 3—July 1996

Dispatch

HIV-1 Group O Virus Identified for the First Time in the United States

M. A. Rayfield*, P. Sullivan†, C. I. Bandea*, L. Britvan‡, R. A. Otten*, C. P. Pau*, D. Pieniazek*, S. Subbarao*, P. Simon†, C. A. Schable*, A. C. Wright*, J. Ward†, and G. Schochetman*
Author affiliations: Author Affiliations: ; *National Center for Infectious Diseases; †National Center for HIV, STD and TB Prevention, Centers for Disease Control and Prevention, Atlanta, Georgia, USA; ‡Kaiser Permanente Medical Group, Los Angeles, California, USA

Main Article

Table 2

Typical peptide reactivity patterns.

Subtype V3-A V3-B V3-C V3-D V3-E V3-F V3-O GP41-M GP41-O
A 2.742 1.144 1.628 0.065 0.083 0.724 0.055 2.683 2.627
B 0.071 1.271 0.051 0.030 0.033 0.038 0.028 2.570 2.414
C 2.320 0.084 2.515 0.079 1.647 1.637 0.061 2.746 2.858
D 0.210 0.079 0.056 1.203 0.048 0.051 0.040 1.380 0.279
E 0.055 0.043 0.385 0.042 1.291 0.038 0.025 0.619 0.340
F 0.062 0.857 0.041 0.037 0.039 0.033 0.037 2.615 2.670
O 0.089 0.088 0.089 0.188 0.088 0.081 1.704 0.070 2.457

GP41-M and GP41-O refer to peptides derived from the consensus gp41 sequences for Group M and Group O variants.

Main Article

1Primers: gag/outer/forward - AGTACATGTTAAAACATGTAGTATGGGC; gag/outer/ reversed - CCTACTCCCTGACAGGCCGT CAGCATTTCTTC; gag/inner/forward - AGTACATGTTAAAACATGTAGTATGGGC; gag/inner/reverse - CCTTAAGCTTTTGT AGAATCTATCTACATA; protease/outer/forward - TTTGCCTCCCTCAAATC; protease/outer/reverse - TTACTGGCACTG GGGCTATGG; protease/inner/ forward - CCTCAAATCCCTCTTTG; protease/inner/reverse - TATAGGGAAGTTTAGTGTACA; env/outer/forward - CACAGAATTTAATGGAACAGGC; env/outer/reverse - TGTGTT ACAATAAAAGAATTCTCC; env/inner/forward - GTTACTTGTACACATGGCAT; and env/inner/reverse - AGAATTCTCCATGACAGTTAAA.

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