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Volume 10, Number 9—September 2004
Research
Genotyping, Orientalis-like Yersinia pestis, and Plague Pandemics
Michel Drancourt*, Véronique Roux*, La Vu Dang*, Lam Tran-Hung*, Dominique Castex†, Viviane Chenal-Francisque‡, Hiroyuki Ogata§, Pierre-Edouard Fournier*, Eric Crubézy¶, and Didier Raoult*
Figure 2
![Molecular detection of Yersinia pestis was achieved in the dental pulp of remains of humans excavated from one Justinian and two Black Death mass graves in France by spacer amplification and sequencing (+, positive polymerase chain reaction [PCR] amplification and sequencing; –, absence of PCR amplification; ND, not done). Sequence analyses showed strains were of Orientalis genotype in all sets of remains; one of them exhibited two mutations numbered according to Y. pestis CO92 strain genome seq](/eid/images/03-0933-F2.gif)
Figure 2. Molecular detection of Yersinia pestis was achieved in the dental pulp of remains of humans excavated from one Justinian and two Black Death mass graves in France by spacer amplification and sequencing (+, positive polymerase chain reaction [PCR] amplification and sequencing; –, absence of PCR amplification; ND, not done)Sequence analyses showed strains were of Orientalis genotype in all sets of remains; one of them exhibited two mutations numbered according to Ypestis CO92 strain genome sequence (GenBank accession noNC-003143)Negative control teeth remained negative.
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