Volume 10, Number 9—September 2004
Research
Experimental Infection of Ground Squirrels (Spermophilus tridecemlineatus) with Monkeypox Virus
Robert B. Tesh*
, Douglas M. Watts*, Elena Sbrana*, Marina Siirin*, Vsevolod L. Popov*, and Shu-Yuan Xiao*
, Douglas M. Watts*, Elena Sbrana*, Marina Siirin*, Vsevolod L. Popov*, and Shu-Yuan Xiao*
Table 2
Results of virus titrations performed on 10% organ suspensions of 10 monkeypox virus–infected ground squirrelsa
| Animal no.b | Liver | Spleen | Kidney | Lung | Heart | Brain |
|---|---|---|---|---|---|---|
| 11 | 7.5a | 6.8 | 4.4 | 5.9 | 3.5 | 2.4 |
| 12 | 7.2 | 6.4 | 4.9 | 6.1 | 3.8 | 1.7 |
| 13 | 7.9 | 6.7 | 5.3 | 5.9 | 4.5 | 1.7 |
| 14 | 7.5 | 6.8 | 5.0 | 6.1 | 3.6 | 2.6 |
| 15 | 7.9 | 6.8 | 4.7 | 6.7 | 4.2 | 4.0 |
| 16 | 7.6 | 6.4 | 4.7 | 6.1 | 4.2 | 2.5 |
| 17 | 7.4 | 6.4 | 4.8 | 5.5 | 3.9 | 2.0 |
| 18 | 7.8 | 6.4 | 5.4 | 6.0 | 4.2 | 2.8 |
| 19 | 7.0 | 6.4 | 4.1 | 5.6 | 4.1 | 2.1 |
| 20 | 7.8 | 6.8 | 4.9 | 6.1 | 5.7 | 1.7 |
aSamples taken at death (necropsy). Virus titer expressed as log10 PFU/mL of 10% tissue suspension.
bAnimals 11–15 were infected intraperitoneally; animals 16–20 were infected intranasally.
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