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Volume 14, Number 10—October 2008


Molecular Surveillance for Multidrug-Resistant Plasmodium falciparum, Cambodia

Naman K. Shah, Alisa P. Alker, Rithy Sem, Agustina Ika Susanti, Sinuon Muth, Jason D. Maguire, Socheat Duong, Frederic Ariey, Steven R Meshnick, and Chansuda WongsrichanalaiComments to Author 
Author affiliations: University of North Carolina School of Public Health, Chapel Hill, North Carolina, USA (N.K. Shah, A.P. Alker, S.R. Meshnick); National Center for Parasitology, Entomology and Malaria Control, Phnom Penh, Cambodia (R. Sem, S. Muth, S. Duong); Pasteur Institute of Cambodia, Phnom Penh, (R. Sem, F. Ariey); US Naval Medical Research Unit No. 2, Jakarta, Indonesia (A.I. Susanti, J.D. Maguire, C. Wongsrichanalai);

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Table 2

Univariate and multivariate linear regression analyses of the association between surveillance site and pfmdr1 copy no., Cambodia

Site No. Mean Univariate linear regression
Multivariate linear regression*
β† 95% CI‡ Predicted mean β† 95% CI‡
Rattanakiri 285 1.09 0 1.03 0
Memut 165 1.09 –0.001 –0.056 to 0.053 1.02 0.047 –0.019 to 0.112
Kampong Seila 10 1.53 –0.234 –0.412 to –0.055 1.35 –0.184 –0.363 to –0.006
Pailin 143 1.70 –0.232 –0.289 to–0.175 1.34 –0.217 –0.276 to –0.159
Chumkiri 109 2.24 –0.393 –0.456 to –0.331 1.72 –0.432 –0.503 to –0.362

*Controlled for parasitemia and year.
†The coefficient estimating the relationship between site and inverse-transformed pfmdr1 copy no.
‡CI, confidence interval.

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