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Volume 15, Number 1—January 2009
Dispatch

Microsporidiosis and Malnutrition in Children with Persistent Diarrhea, Uganda

Siobhan M. MorComments to Author , James K. Tumwine, Elena N. Naumova, Grace Ndeezi, and Saul Tzipori
Author affiliations: Tufts Cummings School of Veterinary Medicine, North Grafton, Massachusetts, USA (S.M. Mor, S. Tzipori); Tufts University School of Medicine, Boston, Massachusetts, USA (S.M. Mor, E.N. Naumova); Makerere University Medical School, Kampala, Uganda (J.K. Tumwine, G. Ndeezi)

Main Article

Table 2

Rate of weight (model 1) and height gain (model 2) in children with and without microsporidiosis when stratified by HIV and Cryptosporidium infection, Uganda*

Model No. Infection status
 Measurement at age:
 R2 Rate (95% CI) Difference† p value‡
Micro Crypto HIV 12 mo 36 mo 60 mo
1a 58 + + 6.63 8.46 9.48 0.27 0.222 (0.13–0.32) −0.147 0.016
1b 19 – + 6.69 10.03 12.11 0.73 0.369 (0.25–0.49)
1c 10 + – 7.60 8.77 9.37 0.28 0.130 (−0.04–0.30) −0.177 0.056
1d 137 – – 6.92 9.70 11.35 0.33 0.307 (0.23–0.38)
1e 55 + + 6.65 7.98 8.69 0.17 0.166 (0.07–0.27) −0.338 <0.001
1f 8 – + 6.50 11.30 14.62 0.82 0.504 (0.27–0.74)
1g 13 + – 7.40 9.50 10.67 0.51 0.227 (0.08–0.37) −0.081
 0.336
1h
 148
 –
 –
6.91
 9.69
 11.34
 0.39
 0.308 (0.25–0.37)
2a 58 + + 69.55 82.83 89.84 0.63 0.159 (0.13–0.19) −0.035 0.123
2b 19 – + 70.46 87.20 96.28 0.82 0.194 (0.15–0.24)
2c 10 + – 71.25 81.47 86.70 0.71 0.122 (0.06–0.19) −0.040 0.206
2d 137 – – 69.17 82.64 89.77 0.55 0.162 (0.14–0.19)
2e 55 + + 69.49 82.03 88.61 0.59 0.151 (0.12–0.19) −0.085 0.009
2f 8 – + 68.75 89.10 100.51 0.81 0.236 (0.12–0.35)
2g 13 + – 71.49 82.73 88.55 0.75 0.133 (0.08–0.18) −0.034 0.240
2h 148 – – 69.41 83.38 90.81 0.61 0.167 (0.15–0.19)

*For ease of interpretation, predicted measurements at various ages are shown in addition to the rate of growth in ln(kg or cm)/ln(months). Micro, microsporidiosis; Crypto, cryptosporidiosis; CI, confidence interval.
†Rate of growth of children with microsporidiosis minus rate of growth of children without microsporidiosis in ln(kg or cm)/ln(months).
‡By t test comparing rate of growth of children with and without microsporidiosis.

Main Article

Page created: November 19, 2010
Page updated: November 19, 2010
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