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Volume 16, Number 6—June 2010


Evolution of Northeastern and Midwestern Borrelia burgdorferi, United States

Dustin BrissonComments to Author , Mary F. Vandermause, Jennifer K. Meece, Kurt D. Reed, and Daniel E. Dykhuizen
Author affiliations: University of Pennsylvania, Philadelphia, Pennsylvania, USA (D. Brisson); Marshfield Clinic Research Foundation, Marshfield, Wisconsin, USA (M.F. Vandermause, J.K. Meece); Northwestern University/Feinberg School of Medicine, Chicago, Illinois, USA (K.D. Reed); Stony Brook University, Stony Brook, New York, USA (D.E. Dykhuizen)

Main Article

Table 1

Genetic markers and population diversity of Borrelia burgdorferi, midwestern and northeastern United States, 1999–2001*

Marker No. samples π dN/dS Maximum χ2, p value Sawyer test, significant fragments
IGS 39 0.014 NA 107, p<0.01 0
ospA 31 0.0033 0.334 0 0
ospB 44 0.0042 0.303 739, p<0.05 0
ospC 44 0.207 0.591 74, 83, 90, 137, 338; p<0.001 4

*dN/dS, directional selection; IGS, intergenic spacer; NA, not applicable; osp, outer surface protein.

Main Article