Volume 18, Number 8—August 2012
CME ACTIVITY - Synopsis
Vaccination of Health Care Workers to Protect Patients at Increased Risk for Acute Respiratory Disease
|Outcome measure and study||Study design||Method of assessment||Measure of effect in patient population||Effect estimate (95% CI)|
|Hayward et al. (27)||Cluster RCT||Reporting by lead nurse||Rate difference, epidemic period 1||−0.02 (−0.05 to 0.02), p = 0.35|
|Rate difference, epidemic period 2||0.00 (−0.03 to 0.04), p = 0.84|
|Rate difference, nonepidemic period 1||0.00 (−0.04 to 0.03), p = 0.80|
|Rate difference, nonepidemic period 2||0.00 (−0.03 to 0.03), p = 0.86|
|Lemaitre et al. (26)||Cluster RCT||Not stated||OR||1.03 (0.76–1.40), p = 0.85|
|Thomas et al. (19)||Pooled data||OR, adjusted for clustering||0.90 (0.66 to 1.21), p = 0.47|
|Hospitalization for respiratory causes: Lemaitre et al. (26)||Cluster RCT||Not stated||OR||1.01 (0.43–2.34), p = 0.98|
|Admissions to hospital with influenza-like illness: Hayward et al. (27)||Cluster RCT||Reporting by lead nurse||Rate difference, epidemic period 1||−0.02 (−0.03 to 0.00), p = 0.009|
|Rate difference, epidemic period 2||0.00 (−0.02 to 0.02), p = 0.99|
|Rate difference, nonepidemic period 1||−0.01 (−0.02 to 0.01), p = 0.32|
|Rate difference, nonepidemic period 2||0.01 (0.00–0.02), p = 0.31|
*RCT, randomized controlled trial; OR, odds ratio. Boldface indicates statistical significance. Shading indicates pooled data.
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