Volume 18, Number 8—August 2012
CME ACTIVITY - Synopsis
Vaccination of Health Care Workers to Protect Patients at Increased Risk for Acute Respiratory Disease
Table 6
Outcome measure and study | Study design | Method of assessment | Measure of effect in patient population | Effect estimate (95% CI) |
---|---|---|---|---|
Hospitalization | ||||
Hayward et al. (27) | Cluster RCT | Reporting by lead nurse | Rate difference, epidemic period 1 | −0.02 (−0.05 to 0.02), p = 0.35 |
Rate difference, epidemic period 2 | 0.00 (−0.03 to 0.04), p = 0.84 | |||
Rate difference, nonepidemic period 1 | 0.00 (−0.04 to 0.03), p = 0.80 | |||
Rate difference, nonepidemic period 2 | 0.00 (−0.03 to 0.03), p = 0.86 | |||
Lemaitre et al. (26) | Cluster RCT | Not stated | OR | 1.03 (0.76–1.40), p = 0.85 |
Thomas et al. (19) | Pooled data | OR, adjusted for clustering | 0.90 (0.66 to 1.21), p = 0.47 | |
Hospitalization for respiratory causes: Lemaitre et al. (26) | Cluster RCT | Not stated | OR | 1.01 (0.43–2.34), p = 0.98 |
Admissions to hospital with influenza-like illness: Hayward et al. (27) | Cluster RCT | Reporting by lead nurse | Rate difference, epidemic period 1 | −0.02 (−0.03 to 0.00), p = 0.009 |
Rate difference, epidemic period 2 | 0.00 (−0.02 to 0.02), p = 0.99 | |||
Rate difference, nonepidemic period 1 | −0.01 (−0.02 to 0.01), p = 0.32 | |||
Rate difference, nonepidemic period 2 | 0.01 (0.00–0.02), p = 0.31 |
*RCT, randomized controlled trial; OR, odds ratio. Boldface indicates statistical significance. Shading indicates pooled data.
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