Volume 19, Number 2—February 2013
CME ACTIVITY - Synopsis
Eastern Equine Encephalitis in Children, Massachusetts and New Hampshire,USA, 1970–2010
Michael A. Silverman, John Misasi, Sandra Smole, Henry A. Feldman, Adam B. Cohen, Sandro Santagata, Michael McManus, and Asim A. Ahmed
Table 5
Colocalization of lesions, virus, and brain inflammation in 2 children in a study of EEE, Massachusetts and New Hampshire, 1970–2010*
| Parameter comparison | Correlation coefficient§ |
|---|---|
| Inflammation vs. EEE virus | 0.82 |
| Inflammation vs. lesion on MRI | 0.68 |
| EEE virus vs. lesion on MRI | 0.52 |
*Lesions were observed by use of MRI (magnetic resonance imaging). EEE, eastern equine encephalitis; –, absent or none found.
†The degree of cerebral inflammation and amount of EEE virus antigen were scored 0–3 on the basis of histopathologic and immunohistopathologic findings.
‡Lesions seen on MRIs were scored 0–3 on the basis of the degree of T2 fluid-attenuated inversion recovery enhancement.
§Determined by using the Pearson correlation.
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