Multisite Validation of Cryptococcal Antigen Lateral Flow Assay and Quantification by Laser Thermal Contrast
David R. Boulware
, Melissa A. Rolfes, Radha Rajasingham, Maximilian von Hohenberg, Zhenpeng Qin, Kabanda Taseera, Charlotte Schutz, Richard Kwizera, Elissa K. Butler, Graeme Meintjes, Conrad Muzoora, John C. Bischof, and David B. Meya
Author affiliations: University of Minnesota, Minneapolis, Minnesota, USA (D.R. Boulware, M.A. Rolfes, R. Rajasingham, M. von Hohenberg, Z. Qin, E.K. Butler, J.C. Bischof, D.B. Meya); Makerere University, Kampala, Uganda (R. Rajasingham, R.K. Kwizera, D.B. Meya); Mbarara University of Science and Technology, Mbarara, Uganda (K. Taseera, C. Muzoora); G.F. Jooste Hospital, Cape Town, South Africa (C. Schutz, G. Meintjes); University of Cape Town, Cape Town (C. Schutz, G. Meintjes)
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Figure 2
Figure 2. . Venn diagram of distribution of 393 cryptococcal meningitis cases tested by 4 diagnostic assays, Uganda and South Africa. CSF, cerebrospinal fluid; CRAG LFA, cryptococcal antigen lateral immunochromatographic flow assay; India ink, India ink microscopy of 1 mL of concentrated CSF specimen. Numbers at the bottom right indicate 2 scenarios in which the Venn diagram does not overlap visually.
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