Seven-Valent Pneumococcal Conjugate Vaccine and Nasopharyngeal Microbiota in Healthy Children
Giske Biesbroek, Xinhui Wang
1, Bart J.F. Keijser
1, Rene M.J. Eijkemans, Krzysztof Trzciński, Nynke Y. Rots, Reinier H. Veenhoven
2, Elisabeth A.M. Sanders, and Debby Bogaert
Author affiliations: University Medical Center Utrecht, Utrecht, the Netherlands (G. Biesbroek, X. Wang, K. Trzciński, E.A.M. Sanders. D. Bogaert); TNO, Zeist, the Netherlands (G. Biesbroek, B.J.F. Keijser); Julius Center for Health Sciences and Primary Care, Utrecht (R.M.J. Eijkemans); Netherlands Vaccine Institute, Bilthoven, the Netherlands (N.Y. Rots); Spaarne Hospital, Hoofddorp, the Netherlands (R.H. Veenhoven)
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Figure 3
Figure 3. Mean absolute abundances of operational taxonomic units (OTUs) in children vaccinated with 7-valent pneumococcal conjugate vaccine and control children at 12 and 24 months of ageThe 25 most abundant OTUs are represented by different colors*OTUs that showed significantly higher abundance in vaccinated children than in controls (p<0.0003)Although not significant, an apparent higher average absolute abundance was observed for Haemophilus and Staphylococcus sppin vaccinated children than in control children at 12 months of age†OTUs that showed a trend toward higher abundance in vaccinated children than in controls (0.0003<p<0.05).
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Page updated: January 17, 2014
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