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Volume 20, Number 5—May 2014
Research

Streptococcus mitis Strains Causing Severe Clinical Disease in Cancer Patients

Samuel A. ShelburneComments to Author , Pranoti Sahasrabhojane, Miguel Saldana, Hui Yao, Xiaoping Su, Nicola Horstmann, Erika Thompson, and Anthony R. Flores
Author affiliations: MD Anderson Cancer Center, Houston, Texas, USA (S.A. Shelburne, P. Sahasrabhojane, M. Saldana, H. Yao, X. Su, N. Horstmann, E. Thompson); Baylor College of Medicine, Houston, Texas, USA (A.R. Flores)

Main Article

Table 3

Relative virulence of viridans group streptococci strains in a neutropenic mouse model*

Strain Streptococcus mitis cluster Pitt bacteremia score of infected patient LD50
SVGS004 3 1 4.1 × 105
SVGS006 2 2 1.6 × 106
SVGS016 2 1 1.4 × 105
SVGS019 1 3 1.9 × 104
SVGS031 2 1 3.6 × 105

*SVGS, Shelburne viridans group streptococcus; LD50, considered, for the purpose of this study, to be the dose at which 50% of the animals nearly died.

Main Article

Page created: April 16, 2014
Page updated: April 16, 2014
Page reviewed: April 16, 2014
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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