Microbiota That Affect Risk for Shigellosis in Children in Low-Income Countries
Brianna Lindsay
, Joe Oundo, M. Anowar Hossain, Martin Antonio, Boubou Tamboura, Alan W. Walker, Joseph N. Paulson, Julian Parkhill, Richard Omore, Abu S.G. Faruque, Suman Kumar Das, Usman N. Ikumapayi, Mitchell Adeyemi, Doh Sanogo, Debasish Saha, Samba Sow, Tamer H. Farag, Dilruba Nasrin, Shan Li, Sandra Panchalingam, Myron M. Levine, Karen Kotloff, Laurence S. Magder, Laura Hungerford, Halvor Sommerfelt, Mihai Pop, James P. Nataro, and O. Colin Stine
Author affiliations: University of Maryland School of Medicine, Baltimore, Maryland, USA (B. Lindsay, T.H. Farag, D. Nasrin, S. Li, S. Panchalingam, M.M. Levine, K. Kotloff, L.S. Magder, L. Hungerford, O.C. Stine); Centers for Disease Control and Prevention/Kenya Medical Research Institute Research Station, Kisumu, Kenya (J. Oundo, R. Omore); International Center for Diarrheal Disease Research, Mirzapur, Bangladesh (M.A. Hossain, A.S.G. Faruque, S.K. Das); Medical Research Council, Basse, The Gambia (M. Antonio, U.N. Ikumapayi, M. Adeyemi, D. Saha); Centre pour le Developpement des Vaccins du Mali, Bamako, Mali (B. Tamboura, D. Sanogo, S. Sow); Wellcome Trust Sanger Institute, Hinxton, UK (A.W. Walker, J. Parkhill); University of Maryland, College Park, Maryland, USA (J.N. Paulson, M. Pop); University of Queensland, Brisbane, Queensland, Australia (S.K. Das); University of Bergen, Bergen, Norway (H. Sommerfelt); Norwegian Institute of Public Health, Bergen (H. Sommerfelt); University of Virginia School of Medicine, Charlottesville, Virginia, USA (J.P. Nataro)
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Figure 4
Figure 4. Shannon diversity index for diarrheal and nondiarrheal samples with high (A) and low (B) levels of Shigella spp. ipaH gene stratified by age group for children in low-income countries. Box and whisker plot indicates distribution of diversity index for each group. The upper whisker extends from the 75th percentile to the highest value that is ≤1.5× the interquartile range (IQR) of the hinge (upper end) or the distance between the first and third quartiles. The lower whisker extends from the hinge (lower end) to the lowest values 1.5× the IQR of the hinge. Diamonds indicate means and horizontal lines indicate medians. Points outside the ends of the whiskers are outliers beyond 1.5× the IQR of the hinge.
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