Skip directly to site content Skip directly to page options Skip directly to A-Z link Skip directly to A-Z link Skip directly to A-Z link
Volume 21, Number 7—July 2015
Dispatch

Hemagglutinin Receptor Binding of a Human Isolate of Influenza A(H10N8) Virus

Irene RamosComments to Author , Mena Mansour, Teddy J. Wohlbold, Megan E. Ermler, Ariana Hirsh, Jonathan A. Runstadler, Ana Fernandez-Sesma, and Florian KrammerComments to Author 
Author affiliations: Icahn School of Medicine at Mount Sinai, New York, New York, USA (I. Ramos, M. Mansour, T.J. Wohlbold, M.E. Ermler, A. Hirsh, A. Fernandez-Sesma, F. Krammer); Massachusetts Institute of Technology, Cambridge Massachusetts, USA (J.A. Runstadler)

Main Article

Figure 1

Receptor binding specificity of hemagglutinin of influenza A(H10N8) virus H10-JD346. A) Binding of recombinant hemagglutinins to glycans in a solid-phase binding assay. Results are means ± SEM of triplicate samples. PAA, polyacrylamide. B) Flow cytometry–based assay. H3-P99 (human), H5-Viet (avian origin isolated from a human case), and H10-mallard (avian) viruses were included in the analysis for comparison and as controls. Values at the top right of the dot plots indicate percentage of cells e

Figure 1. Receptor binding specificity of hemagglutinin of influenza A(H10N8) virus H10-JD346. A) Binding of recombinant hemagglutinins to glycans in a solid-phase binding assay. Results are means ± SEM of triplicate samples. PAA, polyacrylamide. B) Flow cytometry–based assay. H3-P99 (human), H5-Viet (avian origin isolated from a human case), and H10-mallard (avian) viruses were included in the analysis for comparison and as controls. Values at the top right of the dot plots indicate percentage of cells expressing matrix protein 2 (M2). FSC, forward-scattered light; FITC, fluorescein isothiocyanate.

Main Article

Page created: June 15, 2015
Page updated: June 15, 2015
Page reviewed: June 15, 2015
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
file_external