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Volume 22, Number 2—February 2016
Letter

Mycoplasma pneumoniae Monoclonal P1 Type 2c Outbreak, Russia, 2013

Inna Edelstein, Svetlana Rachina, Arabella Touati, Roman Kozlov, Nadège Henin, Cécile Bébéar, and Sabine PereyreComments to Author 
Author affiliations: Smolensk State Medical University of Ministry of Health of Russian Federation, Smolensk, Russian Federation (I. Edelstein, R. Kozlov); Inter-regional Association for Clinical Microbiology & Antimicrobial Chemotherapy, Smolensk (S. Rachina); University of Bordeaux, Bordeaux, France (A. Touati, N. Henin, C. Bébéar, S. Pereyre); Institut National de la Recherche Agronomique, Bordeaux (A. Touati, N. Henin, C. Bébéar, S. Pereyre); Bordeaux University Hospital, Bordeaux (C. Bébéar, S. Pereyre)

Main Article

Table

Characteristics of 61 Mycobacterium pneumoniae–positive respiratory tract specimens collected in Ozerniy, Duchovshina, and the Smolensk region, Russia*

City or region and specimen designation Sample source Patient age, y Hospitalization status Respiratory clinical syndrome Date of collection MLVA type† MLVA type without MPN1‡ PCR-RFLP type Macrolide resistance genotype
Ozerniy
38795 Throat swab 12 Inpatient Pneumonia 2013 Feb 15 53562 (S) 3562 2c Wild type
38796 Throat swab 10 Inpatient Pneumonia 2013 Feb 15 73562 (Y) 3562 2c Wild type
38799 Throat swab 10 Inpatient Pneumonia 2013 Feb 15 73563 3563 2c Wild type
38812 Throat swab 9 Inpatient Pneumonia 2013 Feb 15 73562 (Y) 3562 2c Wild type
38814 Throat swab 11 Inpatient Pneumonia 2013 Feb 15 73562 (Y) 3562 2c Wild type
38941 Throat swab 33 Outpatient Asymptomatic 2013 Feb 20 73563 3563 2c No amp
38945 Throat swab 10 Inpatient Pneumonia 2013 Feb 20 73563 3563 2c No amp
38946 Throat swab 10 Inpatient Pneumonia 2013 Feb 20 73563 3563 2c Wild type
38960 Throat swab 33 Outpatient Asymptomatic 2013 Feb 20 73563 3563 2c Wild type
38962 Throat swab 51 Outpatient Asymptomatic 2013 Feb 20 73562 (Y) 3562 2c Wild type
39042 Throat swab 9 Inpatient Pneumonia 2013 Feb 25 73562 (Y) 3562 2c Wild type
39048 Throat swab 64 Outpatient Asymptomatic 2013 Feb 25 63562 (V) 3562 2c Wild type
39293
 Throat swab
 8
 Inpatient
 Pneumonia
 2013 Mar 7
 73562 (Y)
 3562
 2c
 Wild type
Duchovshina
43593 Throat swab 13 Inpatient Pneumonia 2013 Oct 18 43562 (M) 3562 2c Wild type
43596 Throat swab 15 Outpatient Pneumonia 2013 Oct 18 43562 (M) 3562 2c Wild type
43597 Throat swab 12 Inpatient Pneumonia 2013 Oct 18 43562 (M) 3562 2c Wild type
43692 Throat swab 5 Inpatient Pneumonia 2013 Oct 22 43562 (M) 3562 2c Wild type
43693 Throat swab 10 Inpatient Pneumonia 2013 Oct 23 43562 (M) 3562 2c Wild type
43694 Throat swab 9 Inpatient Pneumonia 2013 Oct 22 43562 (M) 3562 2c Wild type
43695 Throat swab 13 Inpatient Pneumonia 2013 Oct 23 43562 (M) 3562 2c Wild type
43804 Throat swab 9 Inpatient Pneumonia 2013 Oct 27 43562 (M) 3562 2c Wild type
43805 Throat swab 6 Inpatient Pneumonia 2013 Oct 27 43562 (M) 3562 2c Wild type
43806 Throat swab 14 Inpatient Pneumonia 2013 Oct 27 43562 (M) 3562 2c Wild type
43843 Throat swab 6 Inpatient Pneumonia 2013 Oct 30 43562 (M) 3562 2c Wild type
43888 Throat swab 58 Outpatient Pneumonia 2013 Oct 31 43562 (M) 3562 2c Wild type
43890 Throat swab 4 Inpatient Pneumonia 2013 Oct 31 43562 (M) 3562 2c Wild type
43919 Throat swab 41 Outpatient Pneumonia 2013 Nov 1 43562 (M) 3562 2c Wild type
43989 Throat swab 10 Inpatient Pneumonia 2013 Nov 6 43562 (M) 3562 2c Wild type
43990 Throat swab 13 Inpatient Pneumonia 2013 Nov 6 43562 (M) 3562 2c Wild type
43991 Throat swab 8 Inpatient Pneumonia 2013 Nov 6 43562 (M) 3562 2c Wild type
44174 Throat swab 10 Inpatient Pneumonia 2013 Nov 14 43562 (M) 3562 2c Wild type
44176
 Throat swab
 8
 Inpatient
 Pneumonia
 2013 Nov 14
 43562 (M)
 3562
 2c
 No amp
Smolensk region
89 Sputum 17 Inpatient Pneumonia 2006 Oct 24 64572 (X) 4572 1 Wild type
95 Sputum 56 Inpatient Pneumonia 2006 Oct 29 43562 (M) 3562 2a Wild type
108–2 Sputum 19 Inpatient Pneumonia 2006 Nov 3 34572 (J) 4572 1 Wild type
122 Sputum 18 Inpatient Pneumonia 2006 Nov 18 64572 (X) 4572 1 Wild type
164 Sputum 39 Inpatient Pneumonia 2007 Jan 25 34572 (J) 4572 1 Wild type
169 Sputum 43 Inpatient Pneumonia 2007 Feb 4 43562 (M) 3562 2a Wild type
175 Sputum 38 Inpatient Pneumonia 2007 Feb 10 43562 (M) 3562 2a Wild type
186 Sputum 48 Inpatient Pneumonia 2007 Feb 20 4--62§ --62¶ 2a Wild type
187 Sputum 36 Inpatient Pneumonia 2007 Feb 20 33562(G) 3562 2a Wild type
192 Sputum 36 Inpatient Pneumonia 2007 Feb 20 43562 (M) 3562 2a Wild type
191 Sputum 40 Inpatient Pneumonia 2007 Feb 24 43562 (M) 3562 2a Wild type
211 Sputum 43 Inpatient Pneumonia 2007 Mar 21 43562 (M) 3562 2a Wild type
230 Sputum 17 Inpatient Pneumonia 2007 Apr 17 43562 (M) 3562 2a Wild type
257 Sputum 21 Inpatient Pneumonia 2007 Jul 17 43672 3672 1 Wild type
261 Sputum 21 Inpatient Pneumonia 2007 Jul 20 43672 3672 1 Wild type
270 Sputum 19 Inpatient Pneumonia 2007 Jul 30 34572 (J) 4572 1 Wild type
271 Sputum 19 Inpatient Pneumonia 2007 Jul 31 64572 (X) 4572 1 Wild type
280 Sputum 19 Inpatient Pneumonia 2007 Aug 14 64572 (X) 4572 1 Wild type
293 Sputum 20 Inpatient Pneumonia 2007 Sep 11 64572 (X) 4572 1 Wild type
298 Sputum 19 Inpatient Pneumonia 2007 Sep 18 74572 (Z) 4572 1 Wild type
309 Sputum 36 Inpatient Pneumonia 2007 Oct 02 23562 (B) 3562 2a Wild type
310 Sputum 26 Inpatient Pneumonia 2007 Oct 03 33562(G) 3562 2a Wild type
313 Sputum 23 Inpatient Pneumonia 2007 Oct 12 43562 (M) 3562 2a Wild type
292 Sputum 17 Inpatient Pneumonia 2007 Oct 22 33562(G) 3562 2a Wild type
13 Throat swab 23 Inpatient Pneumonia 2010 Feb 21 43562 (M) 3562 2c Wild type
70 Throat swab 62 Inpatient Pneumonia 2010 Mar 18 43562 (M) 3562 2a Wild type
107 Throat swab 33 Inpatient Pneumonia 2010 Mar 26 43562 (M) 3562 2a Wild type
108–1 Throat swab 36 Inpatient Pneumonia 2010 Mar 29 33562(G) 3562 2c Wild type
212 Throat swab 67 Inpatient Pneumonia 2010 Oct 15 24572 (E) 4572 1 Wild type

*MLVA, multilocus variable-number tandem-repeat; no amp, no amplification with the real-time PCR used to detect 23S rRNA mutations associated with macrolide resistance (1); RFLP, restriction fragment length polymorphism. An expanded version of this table is available online at http://wwwnc.cdc.gov/EID/article/22/2/15-1349-T1.htm.
†The profiles are named according to a string of allele numbers in order of MPN1, MPN13, MPN14, MPN15, and MPN16 markers showing the number of repeats at each locus. When available, the naming according to Degrange et al. is shown in parentheses (1).
‡The profiles are named according to a string of allele numbers in order of MPN13, MPN14, MPN15 and MPN16 markers showing the number of repeats at each locus. The instable MPN1 marker (8) was removed.
§Only 3 of 5 loci were amplified. -, indicates no amplification at second and third loci.
¶Only 2 of 4 loci were amplified. -, indicates no amplification at first and second loci.

Main Article

References
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Page created: January 19, 2016
Page updated: January 19, 2016
Page reviewed: January 19, 2016
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