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Volume 22, Number 5—May 2016
Research

Differences in Genotype, Clinical Features, and Inflammatory Potential of Borrelia burgdorferi sensu stricto Strains from Europe and the United States

Tjasa Cerar1, Franc Strle1, Dasa Stupica, Eva Ruzic-Sabljic, Gail McHugh, Allen C. Steere, and Klemen StrleComments to Author 
Author affiliations: University of Ljubljana, Ljubljana, Slovenia (T. Cerar, E. Ruzic-Sabljic); University Medical Center, Ljubljana (F. Strle, D. Stupica); Massachusetts General Hospital, Boston, Massachusetts, USA (G. McHugh, A.S. Steere, K. Strle)

Main Article

Table 2

Characterization of Borrelia burgdorferi sensu stricto strains, by MLST genotyping, from patients in Slovenia and United States*

Genotype No. (%) patients
Slovenia, n = 29 United States, n = 41†
RST1 21 21
OspC type A 0 10
MLST ST1 0 10 (24)
OspC type B 17 11
MLST ST20 6 (20) 0
MLST ST314 6 (20) 0
MLST ST545‡ 5 (17) 0
MLST ST59 0 10 (24)
MLST ST7 0 1 (2)
OspC type Q 2 0
MLST ST20 1 (3) 0
MLST ST546‡ 1 (3) 0
OspC type R 1 0
MLST ST20 1 (3) 0
OspC type M1 1 0
MLST ST20
1 (3)
0
RST2 0 10
OspC type F 0 1
MLST ST8 0 1 (2)
OspC type K 0 7
MLST ST3 0 6 (15)
MLST ST9 0 1 (2)
OspC type N 0 2
MLST ST9
0
2 (5)
RST3 8 10
OspC type D 0 1
MLST ST38 0 1 (2)
OspC type E 0 2
MLST ST19 0 2 (5)
OspC type G 0 2
MLST ST14 0 2 (5)
OspC type I 0 5
MLST ST16 0 5 (12)
OspC type L 7 0
MLST ST24 7 (24) 0
OspC type S 1 0
MLST ST24 1 (3) 0

*MLST, multilocus sequence typing; RST, ribosomal RNA intergenic sequence type; OspC, outer surface protein C; ST, sequence type.
†The 41 isolates from the United States were selected from a larger cohort that were representative of the most common RST/OspC subtypes in the northeastern United States. These isolates included all available OspC type B strains in our collection.
‡New ST.

Main Article

1These authors contributed equally to this article.

Page created: April 13, 2016
Page updated: April 13, 2016
Page reviewed: April 13, 2016
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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