Volume 22, Number 5—May 2016
Research
Differences in Genotype, Clinical Features, and Inflammatory Potential of Borrelia burgdorferi sensu stricto Strains from Europe and the United States
Tjasa Cerar1, Franc Strle1, Dasa Stupica, Eva Ruzic-Sabljic, Gail McHugh, Allen C. Steere, and Klemen Strle
Table 2
Characterization of Borrelia burgdorferi sensu stricto strains, by MLST genotyping, from patients in Slovenia and United States*
| Genotype | No. (%) patients |
|
|---|---|---|
| Slovenia, n = 29 | United States, n = 41† | |
| RST1 | 21 | 21 |
| OspC type A | 0 | 10 |
| MLST ST1 | 0 | 10 (24) |
| OspC type B | 17 | 11 |
| MLST ST20 | 6 (20) | 0 |
| MLST ST314 | 6 (20) | 0 |
| MLST ST545‡ | 5 (17) | 0 |
| MLST ST59 | 0 | 10 (24) |
| MLST ST7 | 0 | 1 (2) |
| OspC type Q | 2 | 0 |
| MLST ST20 | 1 (3) | 0 |
| MLST ST546‡ | 1 (3) | 0 |
| OspC type R | 1 | 0 |
| MLST ST20 | 1 (3) | 0 |
| OspC type M1 | 1 | 0 |
| MLST ST20 |
1 (3) |
0 |
| RST2 | 0 | 10 |
| OspC type F | 0 | 1 |
| MLST ST8 | 0 | 1 (2) |
| OspC type K | 0 | 7 |
| MLST ST3 | 0 | 6 (15) |
| MLST ST9 | 0 | 1 (2) |
| OspC type N | 0 | 2 |
| MLST ST9 |
0 |
2 (5) |
| RST3 | 8 | 10 |
| OspC type D | 0 | 1 |
| MLST ST38 | 0 | 1 (2) |
| OspC type E | 0 | 2 |
| MLST ST19 | 0 | 2 (5) |
| OspC type G | 0 | 2 |
| MLST ST14 | 0 | 2 (5) |
| OspC type I | 0 | 5 |
| MLST ST16 | 0 | 5 (12) |
| OspC type L | 7 | 0 |
| MLST ST24 | 7 (24) | 0 |
| OspC type S | 1 | 0 |
| MLST ST24 | 1 (3) | 0 |
*MLST, multilocus sequence typing; RST, ribosomal RNA intergenic sequence type; OspC, outer surface protein C; ST, sequence type.
†The 41 isolates from the United States were selected from a larger cohort that were representative of the most common RST/OspC subtypes in the northeastern United States. These isolates included all available OspC type B strains in our collection.
‡New ST.
1These authors contributed equally to this article.
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