Added Value of Next-Generation Sequencing for Multilocus Sequence Typing Analysis of a Pneumocystis jirovecii Pneumonia Outbreak1
Elena Charpentier, Cécile Garnaud, Claire Wintenberger, Sébastien Bailly, Jean-Benjamin Murat
2, John Rendu, Patricia Pavese, Thibault Drouet, Caroline Augier, Paolo Malvezzi, Anne Thiébaut-Bertrand, Marie-Reine Mallaret, Olivier Epaulard, Muriel Cornet, Sylvie Larrat, and Danièle Maubon
Author affiliations: Centre Hospitalier Universitaire Grenoble Alpes, Grenoble, France (E. Charpentier, C. Garnaud, C. Wintenberger, J.-B. Murat, J. Rendu, P. Pavese, T. Drouet, C. Augier, P. Malvezzi, A. Thiébaut-Bertrand, M.-R. Mallaret, O. Epaulard, M. Cornet, S. Larrat, D. Maubon); Université Grenoble Alpes, Grenoble (E. Charpentier, C. Garnaud, M.-R. Mallaret, O. Epaulard, M. Cornet, S. Larrat, D. Maubon); Institut National de la Santé et de la Recherche Médicale Université Paris Diderot, Paris, France (S. Bailly).
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Figure 2
Figure 2. Heatmaps representing distribution for mtLSU, CYTB, and SOD variants among patients infected during a Pneumocystis jirovecii pneumonia outbreak at a university hospital in France, 2014–2015. Patients shown in red correspond to cluster patients sharing the common C2a genotype. Patient shown in blue is the patient having the C2a genotype as minor variant (2%). Percentages shown indicate the level of mixed-strain infections for each locus.
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