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Volume 23, Number 8—August 2017
Synopsis

Added Value of Next-Generation Sequencing for Multilocus Sequence Typing Analysis of a Pneumocystis jirovecii Pneumonia Outbreak1

Elena Charpentier, Cécile Garnaud, Claire Wintenberger, Sébastien Bailly, Jean-Benjamin Murat2, John Rendu, Patricia Pavese, Thibault Drouet, Caroline Augier, Paolo Malvezzi, Anne Thiébaut-Bertrand, Marie-Reine Mallaret, Olivier Epaulard, Muriel Cornet, Sylvie Larrat, and Danièle MaubonComments to Author 
Author affiliations: Centre Hospitalier Universitaire Grenoble Alpes, Grenoble, France (E. Charpentier, C. Garnaud, C. Wintenberger, J.-B. Murat, J. Rendu, P. Pavese, T. Drouet, C. Augier, P. Malvezzi, A. Thiébaut-Bertrand, M.-R. Mallaret, O. Epaulard, M. Cornet, S. Larrat, D. Maubon); Université Grenoble Alpes, Grenoble (E. Charpentier, C. Garnaud, M.-R. Mallaret, O. Epaulard, M. Cornet, S. Larrat, D. Maubon); Institut National de la Santé et de la Recherche Médicale Université Paris Diderot, Paris, France (S. Bailly).

Main Article

Table 3

Epidemiologic information on patients found to be carrying the C2a genotype as a major or a minor strain in a study of a Pneumocystis jirovecii pneumonia outbreak at a university hospital in France, 2014–2015

Patient Transmission
 Date of symptom onset Date of diagnosis Time to diagnosis, d Incubation, d
Source Date Place
T2 Index patient ND ND 2014 May 25 2014 May 30 5 ND
T4 T2 12 May 2014  Surgical cardiology outpatient unit 2014 Jul 01 2014 Jul 06 5 49
T5 T2 2014 Apr 18 Kidney transplant unit 2014 Aug 05 2014 Aug 19 14 109
T7† T5 2014 Apr 22 Cardiac echography unit 2014 Oct 09 2014 Oct 29 20 170
T8 T5 2014 Aug 07 Transplant consultation unit 2014 Nov 14 2014 Nov 24 11 99
T10 T8 2014 Nov 23 Transplant consultation unit 2015 Jan 05 2015 Jan 10 5 48

*Date of transmission based on transmission map and previously defined criteria of transmission. ND, not determined.
†Patient carrying the C2a genotype as a minor strain.

Main Article

1Preliminary results from this study were presented at the American Society for Microbiology Microbe 2016 Conference, June 16–20, 2016, Boston, Massachusetts, USA.

2Current affiliation: Centre Hospitalier Universitaire Limoges, Limoges, France.

Page created: July 17, 2017
Page updated: July 17, 2017
Page reviewed: July 17, 2017
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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