Terrestrial Bird Migration and West Nile Virus Circulation, United States
Daniele Swetnam, Steven G. Widen, Thomas G. Wood, Martin Reyna, Lauren Wilkerson, Mustapha Debboun, Dreda A. Symonds, Daniel G. Mead, Barry J. Beaty, Hilda Guzman, Robert B. Tesh, and Alan D.T. Barrett
Author affiliations: University of California at Davis, Davis, California, USA (D. Swetnam); University of Texas Medical Branch, Galveston, Texas, USA (D. Swetnam, S.G. Widen, T.G. Wood, H. Guzman, R.B. Tesh, A.D.T. Barrett); Harris County Public Health, Houston, Texas, USA (M. Reyna, L. Wilkerson, M. Debboun); Chesapeake Mosquito Control Commission, Chesapeake, Virginia, USA (D.A. Symonds); University of Georgia, Athens, Georgia, USA (D.G. Mead); Colorado State University, Fort Collins, Colorado, USA (B.J. Beaty)
Figure 2. Analysis of correlation between virus isolation date and genetic diversity in study of terrestrial bird migration and West Nile virus circulation, United States. Root-to-tip distances of all sequences were determined for each isolate by using the maximum-likelihood tree shown in Figure 1 (https://wwwnc.cdc.gov/EID/article/24/12/18-0382-F1.htm) and plotted against the year. Dots are colored by location of isolation. The correlation between the root-to-tip distance and year of isolation was determined with linear regression shown in blue. 95% CIs are shown in gray. The equation of the linear regression line was used to estimate the year of the most recent common ancestor (MRCA) and the mutation rate (m): y = mx + MRCA.
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