Rat Hepatitis E Virus as Cause of Persistent Hepatitis after Liver Transplant
Siddharth Sridhar, Cyril C.Y. Yip, Shusheng Wu, Jianpiao Cai, Anna Jin-Xia Zhang, Kit-Hang Leung, Tom W.H. Chung, Jasper F.W. Chan, Wan-Mui Chan, Jade L.L. Teng, Rex K.H. Au-Yeung, Vincent C.C. Cheng, Honglin Chen, Susanna K.P. Lau, Patrick C.Y. Woo, Ning-Shao Xia, Chung-Mau Lo, and Kwok-Yung Yuen
Author affiliations: The University of Hong Kong, Hong Kong, China (S. Sridhar, C.C.Y. Yip, S. Wu, J. Cai, A.J.-X. Zhang, K.-H. Leung, T.W.H. Chung, J.F.W. Chan, W.-M. Chan, J.L.L. Teng, R.K.H. Au-Yeung, V.C.C. Cheng, H. Chen, S.K.P. Lau, P.C.Y. Woo, C.-M. Lo, K.-Y. Yuen); The University of Hong Kong–Shenzhen Hospital, Shenzhen, China (J.F.W. Chan, C.-M. Lo, K.-Y. Yuen); Xiamen University, Xiamen, China (N.-S. Xia)
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Figure 3
Figure 3. Histologic and immunohistochemical staining of liver tissue from a 56-year-old man at Queen Mary Hospital, Hong Kong. A, B) Liver tissue sections (original magnification ×200) stained with hematoxylin and eosin obtained at day 0 (A), showing normal hepatocyte architecture, and day 98 (B) after transplant showing progressive increase in hepatocyte ballooning and degenerative changes. C, D) Liver tissue section stained with cross-reactive monoclonal antibody (original magnification ×400); arrows show perinuclear antigen staining (C) and negative control with bovine serum albumin (D).
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