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Volume 24, Number 12—December 2018
Research

Rat Hepatitis E Virus as Cause of Persistent Hepatitis after Liver Transplant

Siddharth Sridhar, Cyril C.Y. Yip, Shusheng Wu, Jianpiao Cai, Anna Jin-Xia Zhang, Kit-Hang Leung, Tom W.H. Chung, Jasper F.W. Chan, Wan-Mui Chan, Jade L.L. Teng, Rex K.H. Au-Yeung, Vincent C.C. Cheng, Honglin Chen, Susanna K.P. Lau, Patrick C.Y. Woo, Ning-Shao Xia, Chung-Mau Lo, and Kwok-Yung YuenComments to Author 
Author affiliations: The University of Hong Kong, Hong Kong, China (S. Sridhar, C.C.Y. Yip, S. Wu, J. Cai, A.J.-X. Zhang, K.-H. Leung, T.W.H. Chung, J.F.W. Chan, W.-M. Chan, J.L.L. Teng, R.K.H. Au-Yeung, V.C.C. Cheng, H. Chen, S.K.P. Lau, P.C.Y. Woo, C.-M. Lo, K.-Y. Yuen); The University of Hong Kong–Shenzhen Hospital, Shenzhen, China (J.F.W. Chan, C.-M. Lo, K.-Y. Yuen); Xiamen University, Xiamen, China (N.-S. Xia)

Main Article

Table 2

Comparison between nucleotide and deduced amino acid sequence identities of HEV strain LCK-3110 and other HEV strains

HEV strain (GenBank accession no.)
 HEV species
 Rat HEV strain LCK-3110
Entire genome
 Nucleotides, %
Amino acids, %
ORF1
 ORF2
 ORF3
 ORF1
 ORF2
 ORF3
Genotype 1 (NC_001434) HEV-A 57.6 56.4 60.9 55.0 50.0 56.3 31.0
Genotype 2 (M74506) HEV-A 57.3 56.3 60.0 50.4 49.7 56.1 27.6
Genotype 3 (EU723512) HEV-A 56.6 55.4 60.7 51.9 50.3 56.5 30.7
Genotype 4 (AJ272108) HEV-A 56.5 55.4 59.8 55.4 49.7 56.4 31.0
Rabbit HEV (FJ906895) HEV-A 56.0 54.9 59.9 51.6 50.1 56.4 27.6
Wild boar HEV (AB573435) HEV-A 57.3 56.2 60.4 54.8 49.7 56.2 33.6
Wild boar HEV (AB602441) HEV-A 56.8 55.7 59.6 54.5 50.3 56.5 31.9
Camel HEV (KJ496144) HEV-A 55.9 54.9 59.4 53.5 50.5 56.2 32.2
Camel HEV (KX387867) HEV-A 55.6 54.3 59.7 53.7 50.1 55.8 29.6
Rat HEV Vietnam-105 (JX120573) HEV-C 93.7 93.3 95.2 96.4 98.2 98.0 95.1
Rat HEV LA-B350 (KM516906) HEV-C 77.3 76.3 79.7 79.3 88.0 92.1 64.7
Ferret HEV (JN998606) HEV-C 68.7 67.5 71.1 64.2 74.8 78.7 45.9
Bat HEV (JQ001749) HEV-D 53.8 53.8 54.3 44.7 45.7 47.9 18.1
Avian HEV (AY535004) HEV-B 53.5 54.0 53.0 46.4 45.6 43.5 24.8

*HEV, hepatitis E virus; ORF, open reading frame.

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Page created: November 20, 2018
Page updated: November 20, 2018
Page reviewed: November 20, 2018
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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