Figure 4. Phylogenetic analysis using complete open reading frame 2 nucleotide sequences of LCK-3110 and other hepatitis E virus strains. The tree was constructed using maximum-likelihood method with bootstrap values calculated from 1,000 trees. Only bootstrap values >70% are shown. GenBank accession numbers are provided. Arrows indicate strain LCK-3110; asterisk indicates strain SRN-02 detected in a street rodent in the epidemiologic investigation. Scale bar indicates mucleotide substitutions per site.