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Volume 24, Number 12—December 2018
Research

Rat Hepatitis E Virus as Cause of Persistent Hepatitis after Liver Transplant

Siddharth Sridhar, Cyril C.Y. Yip, Shusheng Wu, Jianpiao Cai, Anna Jin-Xia Zhang, Kit-Hang Leung, Tom W.H. Chung, Jasper F.W. Chan, Wan-Mui Chan, Jade L.L. Teng, Rex K.H. Au-Yeung, Vincent C.C. Cheng, Honglin Chen, Susanna K.P. Lau, Patrick C.Y. Woo, Ning-Shao Xia, Chung-Mau Lo, and Kwok-Yung YuenComments to Author 
Author affiliations: The University of Hong Kong, Hong Kong, China (S. Sridhar, C.C.Y. Yip, S. Wu, J. Cai, A.J.-X. Zhang, K.-H. Leung, T.W.H. Chung, J.F.W. Chan, W.-M. Chan, J.L.L. Teng, R.K.H. Au-Yeung, V.C.C. Cheng, H. Chen, S.K.P. Lau, P.C.Y. Woo, C.-M. Lo, K.-Y. Yuen); The University of Hong Kong–Shenzhen Hospital, Shenzhen, China (J.F.W. Chan, C.-M. Lo, K.-Y. Yuen); Xiamen University, Xiamen, China (N.-S. Xia)

Main Article

Table 1

Demographic and clinical characteristics of solid organ transplant recipients, Queen Mary Hospital, Hong Kong, January 1, 2014–December 31, 2017*

Characteristic Result†
No. transplant recipients
 518
Organ transplanted
Kidney 430 (83.0)
Liver 61 (11.7)
Heart 16 (3.1)
Lung 10 (1.9)
Combined kidney and liver
 1 (0.2)
Median age, y
 56
Sex
F 203 (39.2)
M
 315 (60.8)
Prevalence of persistent biochemical hepatitis
 52 (10.2)
Cause of biochemical hepatitis
Viral hepatitis‡
Reactivation of chronic HBV infection 5 (9.6)
Chronic HCV infection 7 (13.5)
Chronic HEV infection 5 (9.6)
CMV reactivation 8 (15.4)
Nonviral causes†
Drug toxicity 7 (13.5)
Nonalcoholic fatty liver disease 3 (5.8)
Liver graft rejection 7 (13.5)
Biliary anastomotic stricture 5 (9.6)
Liver malignancies 2 (3.8)
Septic cholestasis 2 (3.8)
Recurrent pyogenic cholangitis 1 (1.9)

*CMV, cytomegalovirus; HBV, hepatitis B virus; HCV, hepatitis C virus; HEV, hepatitis E virus.
†All results are no. (%) unless otherwise indicated.
‡All percentages based on no. patients with biochemical hepatitis.

Main Article

Page created: November 20, 2018
Page updated: November 20, 2018
Page reviewed: November 20, 2018
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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